An update on pacemaking in the myometrium
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley +1 more source
Opposing Effects of Reactive Oxygen Species and Cholesterol on Endothelial Nitric Oxide Synthase and Endothelial Cell Caveolae [PDF]
Timothy E. Peterson+5 more
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Membrane trafficking of synaptic adhesion molecules
Abstract figure legend Synaptic cellular adhesion molecules are surface transmembrane receptors that have been shown to internalize via endocytosis, and possibly also recycle, in a process that has been linked to the function and the turnover of the synaptic contact site.
Cristian A. Bogaciu, Silvio O. Rizzoli
wiley +1 more source
The organisation and functions of local Ca2+ signals [PDF]
Calcium (Ca2+) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation.
Berridge, Michael J.+2 more
core
Localization of Autocrine Motility Factor Receptor to Caveolae and Clathrin-independent Internalization of Its Ligand to Smooth Endoplasmic Reticulum [PDF]
Naciba Benlimame+2 more
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ABSTRACT Human brain tumors were commonly monitored in hospital/clinical laboratories by immunohistochemistry (IHC) technique, which provides major insights into their classification. However, this technique remains laborious and still shows pitfalls. Therefore, the current study was endeavored to reveal the assets of the application of high‐throughput
Kaouthar Louati+16 more
wiley +1 more source
Recent Progress in Gene Delivery Systems Based on Gemini‐Surfactant
Gene delivery is a key area in biomedicine, where nucleic acids are delivered into cells to treat diseases by modulating genes. The low micelle concentration, effective nucleic acid complexation, and low immunogenicity make Gemini surfactants promising gene delivery vectors.
Peng Qian+5 more
wiley +1 more source
Differential Targeting of β-Adrenergic Receptor Subtypes and Adenylyl Cyclase to Cardiomyocyte Caveolae [PDF]
Vitalyi O. Rybin+3 more
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Exosomes in Metabolic Diseases: From Molecular Mechanisms to Clinical Applications
We summarize recent progress in exosome biology and elucidate their roles in interorgan communication networks underlying metabolic pathogenesis. We also comprehensively examine the evolving application of exosomes in metabolic disease management, with a focus on critically evaluating preclinical and clinical advances in exosome‐mediated therapeutic ...
Yanting Wu+3 more
wiley +1 more source
Activated Cardiac Adenosine A1 Receptors Translocate Out of Caveolae [PDF]
Robert D. Lasley+3 more
openalex +1 more source