A novel mutation in isoform 3 of the plasma membrane Ca2+ pump impairs cellular Ca2+ homeostasis in a patient with cerebellar ataxia and laminin subunit 1\u3b1 mutations. [PDF]
, 2015 The particular importance of Ca2+ signaling to neurons demands its precise regulation within their cytoplasm. Isoform 3 of the plasma membrane Ca2+ ATPase (the PMCA3 pump), which is highly expressed in brain and cerebellum, plays an important role in the
Brini, Marisa +9 more
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From Skin to Nerve: Mapping Tissue‐Specific Innovations in Gelatin–Dopamine Hydrogel Platforms
Journal of Biomedical Materials Research Part A, Volume 114, Issue 2, February 2026.Gelatin and dopamine as interacting building blocks for functional tissue applications. ABSTRACT The biomimetic adhesive qualities, biocompatibility, and multifunctionality of biomaterials containing gelatin and dopamine have propelled them to the forefront of regenerative medicine.
Andreea I. Dinu +3 more
wiley +1 more source
Editor's evaluation: Caveolae couple mechanical stress to integrin recycling and activation
, 2022 Suzanne R. Pfeffer
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Microscopy Research and Technique, Volume 89, Issue 2, Page 260-272, February 2026.A newly established 3D correlative cryogenic fluorescence microscopy, focused ion beam scanning electron microscopy, and soft x‐ray tomography workflow allowed for enough contrast and resolution to quantify the intracellular uptake of zirconyl‐containing inorganic–organic hybrid nanoparticles as a novel chemotherapeutic drug delivery system into ...
Pavitra Sokke Rudraiah +7 more
wiley +1 more source
Interactions between proteins bound to biomembranes
, 2003 We study a physical model for the interaction between general inclusions bound to fluid membranes that possess finite tension, as well as the usual bending rigidity. We are motivated by an interest in proteins bound to cell membranes that apply forces to
A. Albersdorfer +39 more
core +1 more source
Caveolins/caveolae protect adipocytes from fatty acid-mediated lipotoxicity
Journal of Lipid Research, 2011 Mice and humans lacking functional caveolae are dyslipidemic and have reduced fat stores and smaller fat cells. To test the role of caveolins/caveolae in maintaining lipid stores and adipocyte integrity, we compared lipolysis in caveolin-1 (Cav1)-null ...
Tova Meshulam +4 more
doaj +1 more source
The Subgingival Host–Microbial Landscape in Mothers With Periodontitis and Their At‐Risk Offspring
Journal of Clinical Periodontology, Volume 53, Issue 2, Page 201-213, February 2026.ABSTRACT Aim To evaluate the subgingival proteome and microbiome of mothers with periodontitis and their offspring, thereby assessing signatures of periodontal diseases. Methods Forty participants in four groups were included: mothers with periodontitis and their offspring, as well as periodontally healthy mothers and their offspring.
Hélvis E. S. Paz +8 more
wiley +1 more source
Journal of Applied Polymer Science, Volume 143, Issue 4, January 20, 2026.ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares +4 more
wiley +1 more source
Regulation of caveolin and caveolae by cholesterol in MDCK cells
Journal of Lipid Research, 1998 We have examined the expression of caveolin in MDCK cells under conditions that vary cellular cholesterol concentration. Caveolin mRNA levels dropped to one-sixth of control levels after treatment with simvastatin, an inhibitor of cholesterol synthesis ...
Deborah Hailstones +3 more
doaj +1 more source
Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium [PDF]
, 1998 Phil Oh +2 more
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