Results 71 to 80 of about 44,977 (257)
The alternate GNB3 splice variant, Gβ3s, exhibits an altered signalling response to EGF stimulation, which leads to enhanced cell migration [PDF]
, 2013 It has recently been reported that the duplication of the GNB3 gene has been shown to be directly linked to an obesity phenotype, both in humans and also in a humanised mouse model. Moreover, the common human GNB3 c.825C>T polymorphism (rs5443) causes
D’Ascanio, Isabella +7 more
core +5 more sources
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.SuperResNET is a powerful integrated software that reconstructs network architecture and molecular distribution of subcellular structures from single molecule localization microscopy datasets. SuperResNET segments the nuclear pore complex and corners, extracts size, shape, and network features of all segmented nuclear pores and uses modularity analysis
Yahongyang Lydia Li +6 more
wiley +1 more source
The Journal of Cell Biology, 2008 ![Graphic][1] When the sodium pump is scarce, Cav1 (green) loiters near the nucleus instead of infiltrating the cell membrane. The sodium pump is branching out. As [Cai et al.][2] show, the pump not only moves ions, it controls trafficking of a membrane protein that is crucial ...
openaire +3 more sources
Gold Nanoclusters as Smart Nanoplatforms for Targeted Cancer Therapy
Advanced NanoBiomed Research, EarlyView.A folic acid‐targeted gold nanocluster platform is developed for tumor‐specific delivery and radiofrequency (RF)‐triggered release of doxorubicin. Enhanced uptake, nuclear localization, and therapeutic efficacy are confirmed in 2D and 3D spheroid models.
Samad Mussa Farkhani +6 more
wiley +1 more source
Nanoparticles Functionalized with Polymer Brushes for Gene Delivery
Advanced NanoBiomed Research, EarlyView.The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley +1 more source
Mechanism of Oxygen "buffering" by Caveolae
, 2022 The ‘oxygen paradox’ can be explained as two opposing biological processes with oxygen (O2) as a reactant. On the one hand, oxygen is essential to aerobic metabolism, being used by mitochondria to fuel oxidative phosphorylation. On the other hand, an excess supply of oxygen will generate reactive species which are harmful for the cell.
Davoudi, Samaneh +4 more
openaire +3 more sources
Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges
Advanced NanoBiomed Research, EarlyView.Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou +7 more
wiley +1 more source
Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1 [PDF]
, 2006 The directional flow of the plant hormone auxin mediates multiple developmental processes, including patterning and tropisms. Apical and basal plasma membrane localization of AUXIN-RESISTANT1 (AUX1) and PIN-FORMED1 (PIN1) auxin transport components ...
Bennett, Malcolm +4 more
core +2 more sources
Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells [PDF]
, 2005 Cathepsin B and pro-urokinase plasminogen activator (pro-uPA) localize to the caveolae of HCT 116 human colorectal carcinoma cells, an association mediated by active K-RAS.
Cavallo-Medved, Dora +4 more
core +2 more sources