Results 11 to 20 of about 56,717 (240)
The Caveolin-1 Connection to Cell Death and Survival [PDF]
Current Molecular Medicine, 2013 Nunez, S (Nunez, S.)[ 1,4 ] 1. Fac Med, CEMC, Lab Comunicac Celulares, Santiago, Chile. 4. Univ Talca, Fac Hlth Sci, Talca, ChileCaveolins are a family of membrane proteins required for the formation of small plasma membrane invaginations called caveolae
Aguirre, A. +8 more
core +14 more sources
Caveolin-1 Is a Critical Determinant of Autophagy, Metabolic Switching, and Oxidative Stress in Vascular Endothelium [PDF]
, 2014 Caveolin-1 is a scaffolding/regulatory protein that interacts with diverse signaling molecules. Caveolin-1null mice have marked metabolic abnormalities, yet the underlying molecular mechanisms are incompletely understood. We found the redox stress plasma
Kalwa, Hermann +7 more
core +20 more sources
Caveolin-1, caveolae, and glioblastoma [PDF]
Neuro-Oncology, 2012 Glioblastoma multiforme (GBM) is the most common malignant brain tumor and is characterized by high invasiveness, poor prognosis, and limited therapeutic options. Biochemical and morphological experiments have shown the presence of caveolae in glioblastoma cells. Caveolae are flask-shaped plasma membrane subdomains that play trafficking, mechanosensing,
Parat, Marie-Odile, Riggins, Gregory J.
openaire +4 more sources
Involvement of caveolin-1 in skin diseases
Frontiers in Immunology, 2022 The skin is the outermost layer and largest organ in the human body. Since the skin interfaces with the environment, it has a variety of roles, including providing a protective barrier against external factors, regulating body temperature, and retaining water in the body.
Naoko Takamura, Yukie Yamaguchi
openaire +3 more sources
Caveolin‐1, cancer and therapy resistance [PDF]
International Journal of Cancer, 2018 Resistance of solid tumors to chemo‐ and radiotherapy remains a major obstacle in anti‐cancer treatment. Herein, the membrane protein caveolin‐1 (CAV1) came into focus as it is highly expressed in many tumors and high CAV1 levels were correlated with tumor progression, invasion and metastasis, and thus a worse clinical outcome.
Julia Ketteler, Diana Klein
openaire +3 more sources
The Biomarker Potential of Caveolin-1 in Penile Cancer [PDF]
Frontiers in Oncology, 2021 Various types of human cancers were characterized by an altered expression of epithelial or stromal caveolin-1 (CAV1). However, the clinical significance of CAV1 expression in penile cancer remains largely unknown. Here the expression patterns of CAV1 were analyzed in a retrospective cohort (n=43) of penile squamous cell carcinomas (SCC).
Panic, Andrej +6 more
openaire +7 more sources
Caveolin-1 Signaling in Lung Fibrosis [PDF]
The Open Rheumatology Journal, 2012 Caveolin-1 is a master regulator of several signaling cascades because it is able to bind to and thereby inhibit members of a variety of kinase families. While associated with caveolae and involved in their generation, caveolin-1 is also present at other sites.
Elena Tourkina, Stanley Hoffman
openaire +3 more sources
Lifestyle intervention in individuals with impaired glucose regulation affects Caveolin-1 expression and DNA methylation [PDF]
, 2020 © 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impaired ...
Adam, S. +9 more
core +1 more source
Decreased expression of caveolin 1 in patients with systemic sclerosis: crucial role in the pathogenesis of tissue fibrosis. [PDF]
, 2008 OBJECTIVE: Recent studies have implicated caveolin 1 in the regulation of transforming growth factor beta (TGFbeta) downstream signaling. Given the crucial role of TGFbeta in the pathogenesis of systemic sclerosis (SSc), we sought to determine whether ...
de Almeida, Cecilia J. +6 more
core +2 more sources
Caveolin-1 Associated Adenovirus Entry into Human Corneal Cells [PDF]
, 2014 The cellular entry of viruses represents a critical area of study, not only for viral tropism, but also because viral entry dictates the nature of the immune response elicited upon infection.
Chintakuntlawar, Ashish V. +7 more
core +1 more source