Results 31 to 40 of about 72,924 (237)

Caveolin-1 expression is elevated in claudin-low mammary tumor cells

open access: yesCancer Cell International, 2012
Background Caveolin-1 is a scaffolding protein found in plasma membrane invaginations known as caveolae. Caveolin-1 can regulate a number of intracellular processes such as signal transduction, cholesterol metabolism and vesicular transport. With respect
Thompson Devan E   +2 more
doaj   +1 more source

Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]

open access: yes, 2014
Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L   +11 more
core   +2 more sources

Caveolin-1 in Tumour Cells is Predominately Expressed in the Basal Subtype of Triple-Negative Breast Carcinoma [PDF]

open access: yesJournal of Biomedical & Clinical Research, 2014
Triple-negative breast cancer (TNBC) is a subtype of breast cancer which is clinically negative for expression of steroid hormones and HER2 protein.
Savelina Popovska   +2 more
doaj   +3 more sources

Pathophysiological Role of Caveolae in Hypertension [PDF]

open access: yes, 2019
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver   +4 more
core   +2 more sources

Caveolae/Caveolin-1 Are Important Modulators of Store-Operated Calcium Entry in Hs578/T Breast Cancer Cells

open access: yesJournal of Pharmacological Sciences, 2008
Caveolin-1 is a principal component of caveolae, invaginations of the plasma membrane that are enriched in cholesterol and sphingolipids. The expression of caveolin-1 has been shown to be tightly correlated to the progression of breast cancer tumors ...
Hua Zhu   +4 more
doaj   +1 more source

C-Terminal Region of Caveolin-3 Contains a Stretch of Amino Acid Residues Capable of Diminishing Symptoms of Experimental Autoimmune Encephalomyelitis but Not Rheumatoid Arthritis Modeled in Rats

open access: yesBiomedicines, 2023
A short synthetic peptide from the C-terminal part of the caveolin-3 structure was tested for experimental autoimmune encephalomyelitis (EAE) treatment in rats.
Alexey V. Danilkovich   +18 more
doaj   +1 more source

Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]

open access: yes, 2020
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T   +11 more
core   +1 more source

Identification of Caveolin and Caveolin-Related Proteins in the Brain [PDF]

open access: yesThe Journal of Neuroscience, 1997
Caveolae are 50–100 nm, nonclathrin-coated, flask-shaped plasma membrane microdomains that have been identified in most mammalian cell types, except lymphocytes and neurons. To date, multiple functions have been ascribed to caveolae, including the compartmentalization of lipid and protein components that function in transmembrane signaling events ...
P L, Cameron   +4 more
openaire   +2 more sources

Factors Affecting Spontaneous Endocytosis and Survival of Probiotic Lactobacilli in Human Intestinal Epithelial Cells

open access: yesMicroorganisms, 2022
Mutualistic bacteria have different forms of interaction with the host. In contrast to the invasion of pathogenic bacteria, naturally occurring internalization of commensal bacteria has not been studied in depth.
Diana Aurora Ramirez-Sánchez   +5 more
doaj   +1 more source

Decreased urothelial expression of caveolin 1 and 2 in aging rats showing detrusor overactivity: Potential association with aging bladder [PDF]

open access: yesInvestigative and Clinical Urology, 2021
Purpose: The purpose of this study was to investigate the effect of aging on bladder function and caveolin protein expression in rat urothelium. Materials and Methods: Female Sprague-Dawley rats were divided into the following two groups: young age ...
Jae Hyeon Kim   +2 more
doaj   +1 more source

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