Results 31 to 40 of about 72,924 (237)
Caveolin-1 expression is elevated in claudin-low mammary tumor cells
Background Caveolin-1 is a scaffolding protein found in plasma membrane invaginations known as caveolae. Caveolin-1 can regulate a number of intracellular processes such as signal transduction, cholesterol metabolism and vesicular transport. With respect
Thompson Devan E +2 more
doaj +1 more source
Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]
Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L +11 more
core +2 more sources
Caveolin-1 in Tumour Cells is Predominately Expressed in the Basal Subtype of Triple-Negative Breast Carcinoma [PDF]
Triple-negative breast cancer (TNBC) is a subtype of breast cancer which is clinically negative for expression of steroid hormones and HER2 protein.
Savelina Popovska +2 more
doaj +3 more sources
Pathophysiological Role of Caveolae in Hypertension [PDF]
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver +4 more
core +2 more sources
Caveolin-1 is a principal component of caveolae, invaginations of the plasma membrane that are enriched in cholesterol and sphingolipids. The expression of caveolin-1 has been shown to be tightly correlated to the progression of breast cancer tumors ...
Hua Zhu +4 more
doaj +1 more source
A short synthetic peptide from the C-terminal part of the caveolin-3 structure was tested for experimental autoimmune encephalomyelitis (EAE) treatment in rats.
Alexey V. Danilkovich +18 more
doaj +1 more source
Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T +11 more
core +1 more source
Identification of Caveolin and Caveolin-Related Proteins in the Brain [PDF]
Caveolae are 50–100 nm, nonclathrin-coated, flask-shaped plasma membrane microdomains that have been identified in most mammalian cell types, except lymphocytes and neurons. To date, multiple functions have been ascribed to caveolae, including the compartmentalization of lipid and protein components that function in transmembrane signaling events ...
P L, Cameron +4 more
openaire +2 more sources
Mutualistic bacteria have different forms of interaction with the host. In contrast to the invasion of pathogenic bacteria, naturally occurring internalization of commensal bacteria has not been studied in depth.
Diana Aurora Ramirez-Sánchez +5 more
doaj +1 more source
Decreased urothelial expression of caveolin 1 and 2 in aging rats showing detrusor overactivity: Potential association with aging bladder [PDF]
Purpose: The purpose of this study was to investigate the effect of aging on bladder function and caveolin protein expression in rat urothelium. Materials and Methods: Female Sprague-Dawley rats were divided into the following two groups: young age ...
Jae Hyeon Kim +2 more
doaj +1 more source

