Results 91 to 100 of about 27,120 (180)
Drug Testing and Analysis, Volume 18, Issue 3, Page 334-340, March 2026.MDMB‐5Br‐PINACA, a novel synthetic cannabinoid, was identified and structurally characterized in seized herbal products using GC‐MS, LC‐HRMS, and NMR. The discovery underscores ongoing diversification of SCs and the need for vigilant surveillance.
Alexandre Barcia de Godoi +6 more
wiley +1 more source
Developmental Dynamics, Volume 255, Issue 3, Page 321-339, March 2026.Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino +3 more
wiley +1 more source
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.Abstract Background Cannabis contains various cannabinoids, with Δ9‐tetrahydrocannabinol (Δ9‐THC) being the primary psychoactive compound. A non‐psychoactive precursor called Δ9‐tetrahydrocannabinolic acid (THC‐A) is converted to Δ9‐THC slowly over time or rapidly when heated. Cannabis use is linked to psychotic outcomes, with increased risk associated
Daniel Greer +2 more
wiley +1 more source
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
Small, Volume 22, Issue 16, 17 March 2026.The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho +10 more
wiley +1 more source
Single oral administration of dronabinol increases ocular blood flow in patients with glaucoma
Acta Ophthalmologica, Volume 104, Issue 2, Page 225-232, March 2026.Abstract Purpose Glaucoma is a leading cause of irreversible blindness globally, primarily driven by elevated intraocular pressure (IOP). Still, some patients progress despite significant IOP lowering, potentially due to impaired ocular blood flow. This study aimed to evaluate the effects of dronabinol, a synthetic tetrahydrocannabinol derivative, on ...
Theresa Lindner +9 more
wiley +1 more source
Obesity Reviews, Volume 27, Issue 3, March 2026.ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia +5 more
wiley +1 more source
EFSA Journal, Volume 24, Issue 3, March 2026.Abstract Following an application from Anxiofit Ltd. pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of Hungary, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked for an opinion on the scientific substantiation of a health claim related to Anxiofit‐1 and reduction of subthreshold and mild ...
EFSA Panel on Nutrition +17 more
wiley +1 more source
mGluR5, CB1 and neuroprotection
Oncotarget, 2016 Carvalho, Toniana G. +2 more
openaire +2 more sources
Unraveling Endocannabinoid Signaling Pathways in Cisplatin‐Induced Ototoxicity
The FASEB Journal, Volume 40, Issue 4, 28 February 2026.We performed a comprehensive molecular profiling of the endocannabinoid (eCB) system (ECS) in an auditory Hair cell (HC)‐like cell line (1). Afterwards, we developed suitable in vitro and in vivo models of cisplatin‐induced ototoxicity where we identified distinct components of the ECS (CB2R, DAGLβ and ABHD6) as molecular targets of the drug (2 ...
Sakthimala Palaniappan +12 more
wiley +1 more source