Results 31 to 40 of about 27,120 (180)

Reversible disruption of pre-pulse inhibition in hypomorphic-inducible and reversible CB1-/- mice. [PDF]

PLoS ONE, 2012
Although several genes are implicated in the pathogenesis of schizophrenia, in animal models for such a severe mental illness only some aspects of the pathology can be represented (endophenotypes).
Maria Franca Marongiu, Daniela Poddie, Susanna Porcu, Maria Francesca Manchinu, Maria Paola Castelli, Valeria Sogos, Valentina Bini, Roberto Frau, Elisabetta Caredda, Maria Collu, Maria Serafina Ristaldi   +10 more
doaj   +1 more source

A Fully Soft Sensing Suit With Optimal Sensor Placement for Real‐Time Motion Tracking

Advanced Intelligent Systems, EarlyView.
A fully soft, skin‐conformable sensing suit integrating stretchable sensors, liquid metal wiring, and soft electrodes was developed using direct ink writing, with sensor placement optimized through an automated algorithmic pipeline. This system enables accurate and unobtrusive real‐time motion tracking, providing a scalable, material‐based solution to ...
Jinhyeok Oh, Joonbum Bae
wiley   +1 more source

Hepatic expression of cannabinoid receptors CB1 and CB2 correlate with fibrogenesis in patients with chronic hepatitis B

International Journal of Infectious Diseases, 2017
Background: The endocannabinoid system is involved in the pathogenesis of liver fibrosis. However, most of the findings in this area have come from experimental studies in animal models or clinical trials on chronic hepatitis C.
Erhei Dai, Lianshan Zhang, Lihong Ye, Shiqing Wan, Lulu Feng, Qi Qi, Fang Yao, Zhen Li   +7 more
doaj   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

Gut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei, Xin‐Wei Sun, Hao‐Jie Huang, Yu‐Zhi Zhao, Shuang‐Jiang Liu, Chang Liu   +5 more
wiley   +1 more source

Differential expression of brain cannabinoid receptors between repeatedly stressed males and females may play a role in age and gender-related difference in traumatic brain injury: Implications from animal studies

Frontiers in Neurology, 2014
Inconsistent gender differences in the outcome of TBI have been reported. The mechanism is unknown. In a recent male animal study, repeated stress followed by TBI had synergistic effects on brain gene expression and caused greater behavioral deficits ...
Guoqiang eXing, Guoqiang eXing, Janis eCarlton, Xiaolong eJiang, Jillian eWen, Jillian eWen, Min eJia, He eLi   +7 more
doaj   +1 more source

Holocene sea‐level and environmental changes on the Isle of Mull, Scotland

Journal of Quaternary Science, EarlyView.
ABSTRACT Sea‐level and coastal changes are reconstructed on the Isle of Mull, western Scotland, from 10 988 to 10 507 cal BP to the present. This research has produced the first SLIP for the Isle of Mull. A multiproxy approach including pollen, spore, foraminifera and diatom analyses reveals palaeoenvironmental changes from two coastal sites.
Katherine A. Selby, Jane Wheeler, William E. N. Austin, Heather Austin, Tom Hill, Sarah L. Bradley, Sally Derrett   +6 more
wiley   +1 more source

Expression of cannabinoid 1 and, 2 receptors and the effects of cannabinoid 1 and, 2 receptor agonists on detrusor overactivity associated with bladder outlet obstruction in rats

BMC Urology, 2017
Background This study investigated changes in the expression of cannabinoid (CB) receptors and the effects of CB1 and CB2 agonists on detrusor overactivity (DO) associated with bladder outlet obstruction (BOO) in rats.
Sung Dae Kim, Kang Jun Cho, Joon Chul Kim   +2 more
doaj   +1 more source

Traditional Chinese Medicine as an Integrative Adjunct in Oncology Perioperative Practice: Analgesia, Immune Modulation, and Translational Challenges

Medicine Bulletin, EarlyView.
ABSTRACT Traditional Chinese medicine (TCM), including herbal analgesic adjuvants and acupuncture‐based interventions, has gained increasing attention as an integrative strategy for perioperative pain management in oncology. Bioactive phytochemicals—such as terpenoids, flavonoids, alkaloids, and polyphenols—exert multimodal pharmacological effects ...
Yuqin Tang, Zheng Luo, Xu Zhao, Yongqiang Zhang, Mingyang Sun, Jiaqiang Zhang   +5 more
wiley   +1 more source

Effect of CB1 Receptor Deficiency on Mitochondrial Quality Control Pathways in Gastrocnemius Muscle

Biology
This study aims to explore the complex role of cannabinoid type 1 receptor (CB1) signaling in the gastrocnemius muscle, assessing physiological processes in both CB1+/+ and CB1−/− mice.
Rosalba Senese, Giuseppe Petito, Elena Silvestri, Maria Ventriglia, Nicola Mosca, Nicoletta Potenza, Aniello Russo, Francesco Manfrevola, Gilda Cobellis, Teresa Chioccarelli, Veronica Porreca, Vincenza Grazia Mele, Rosanna Chianese, Pieter de Lange, Giulia Ricci, Federica Cioffi, Antonia Lanni   +16 more
doaj   +1 more source