Results 11 to 20 of about 27,782 (204)
High spatio-temporal resolution pollutant measurements of on-board vehicle emissions using ultra-fast response gas analyzers [PDF]
Atmospheric Measurement Techniques, 2018 Existing ultra-fast response engine exhaust emissions analyzers have been adapted for on-board vehicle use combined with GPS data. We present, for the first time, how high spatio-temporal resolution data products allow transient features associated ...
M. Irwin +5 more
doaj +1 more source
The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra. [PDF]
PLoS ONE, 2018 Presynaptic cannabinoid-1 receptors (CB1-R) bind endogenous and exogenous cannabinoids to modulate neurotransmitter release. CB1-Rs are expressed throughout the basal ganglia, including striatum and substantia nigra, where they play a role in learning ...
Margaret I Davis +7 more
doaj +1 more source
Suppression of CB1 cannabinoid receptor by lentivirus mediated small interfering RNA ameliorates hepatic fibrosis in rats. [PDF]
PLoS ONE, 2012 It is recognized that endogenous cannabinoids, which signal through CB1 receptors in hepatic stellate cells (HSCs), exert a profibrotic effect on chronic liver diseases. In this study, we suppressed CB1 expression by lentivirus mediated small interfering
Si-Wen Chen +7 more
doaj +1 more source
Frontiers in Neuroanatomy, 2022 Adult oligodendrocyte progenitor cells (OPCs) give rise to myelinating oligodendrocytes through life and play crucial roles in brain homeostasis and plasticity during health and disease.
Andrea Manterola +18 more
doaj +1 more source
Toxicological properties of Δ9-tetrahydrocannabinol and cannabidiol
Arhiv za Higijenu Rada i Toksikologiju, 2020 Cannabis sativa L. contains more than 100 phytocannabinoids that can interact with cannabinoid receptors CB1 and CB2. None of the cannabinoid receptor ligands is entirely CB1- or CB2-specific. The effects of cannabinoids therefore differ not just because
Černe Katarina
doaj +1 more source
Molecules, 2021 Numerous studies have investigated the roles of the type 1 cannabinoid receptor (CB1) in glutamatergic and GABAergic neurons. Here, we used the cell-type-specific CB1 rescue model in mice to gain insight into the organizational principles of plasma ...
Miquel Saumell-Esnaola +6 more
doaj +1 more source
The CB1 Receptor as the Cornerstone of Exostasis [PDF]
Neuron, 2017 The type-1 cannabinoid receptor (CB1) is the main effector of the endocannabinoid system (ECS), which is involved in most brain and body functions. In this Perspective, we provide evidence indicating that CB1 receptor functions are key determinants of bodily coordinated exostatic processes.
Pier Vincenzo Piazza +2 more
openaire +2 more sources
Frontiers in Behavioral Neuroscience, 2021 Cannabinoid receptors 1 and 2 (CB1 and CB2, respectively) play an important role in maintaining the integrity of the blood–brain barrier (BBB). On the other hand, BBB dysfunction is a common feature in drug-resistant epilepsy.
María de los Ángeles Nuñez-Lumbreras +12 more
doaj +1 more source
Expression and functional relevance of cannabinoid receptor 1 in Hodgkin lymphoma. [PDF]
PLoS ONE, 2013 Cannabinoid receptor 1 (CB1) is expressed in certain types of malignancies. An analysis of CB1 expression and function in Hodgkin lymphoma (HL), one of the most frequent lymphomas, was not performed to date.We examined the distribution of CB1 protein in ...
Alexander H Benz +10 more
doaj +1 more source
Loss of cannabinoid receptor CB1 induces preterm birth. [PDF]
PLoS ONE, 2008 Preterm birth accounting approximate 10% of pregnancies in women is a tremendous social, clinical and economic burden. However, its underlying causes remain largely unknown.
Haibin Wang, Huirong Xie, Sudhansu K Dey
doaj +1 more source