The roles of CC chemokines in response to radiation [PDF]
Radiation Oncology, 2022 Radiotherapy is an effective regimen for cancer treatment alone or combined with chemotherapy or immunotherapy. The direct effect of radiotherapy involves radiation-induced DNA damage, and most studies have focused on this area to improve the efficacy of
Lei Wang +4 more
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CC Chemokines in Idiopathic Pulmonary Fibrosis: Pathogenic Role and Therapeutic Potential [PDF]
Biomolecules, 2023 Idiopathic pulmonary fibrosis (IPF), characterized by progressive worsening of dyspnea and irreversible decline in lung function, is a chronic and progressive respiratory disease with a poor prognosis.
Shanshan Liu +4 more
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Identification of prognostic and therapeutic value of CC chemokines in Urothelial bladder cancer: evidence from comprehensive bioinformatic analysis [PDF]
BMC Urology, 2021 Background Urothelial bladder cancer (BC) is one of the most prevalent malignancies with high mortality and high recurrence rate. Angiogenesis, tumor growth and metastasis of multiple cancers are partly modulated by CC chemokines. However, we know little
Yuxin Li +8 more
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CC chemokines and receptors in osteoarthritis: new insights and potential targets [PDF]
Arthritis Research & Therapy, 2023 Osteoarthritis (OA) is a prevalent degenerative disease accompanied by the activation of innate and adaptive immune systems-associated inflammatory responses.
Yuchen Zhang +5 more
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Serum CC Chemokines as Potential Biomarkers for the Diagnosis of Major Depressive Disorder [PDF]
Psychology Research and Behavior Management, 2022 Wenfan Gao,1– 4,* Yayun Xu,5– 7,* Jun Liang,1– 4 Yanhong Sun,1– 4 Yuanyuan Zhang,1– 4 Feng Shan,1– 4 Jinfang Ge,6– 8 Qingrong Xia1– 4 1Affiliated Psychological Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department ...
Gao W +7 more
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CC chemokines Modulate Immune responses in Pulmonary Hypertension [PDF]
Journal of Advanced ResearchBackground: Pulmonary hypertension (PH) represents a progressive condition characterized by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and increased mortality rates. Substantial evidence has elucidated the pivotal
Qian Yan +11 more
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Role of CC Chemokines Subfamily in the Platinum Drugs Resistance Promotion in Cancer [PDF]
Frontiers in Immunology, 2020 Cancer is a significant medical issue, being one of the main causes of mortality around the world. The therapies for this pathology depend on the stage in which the cancer is found, but it is usually diagnosed at an advanced stage in which the treatment ...
Maria E. Reyes +5 more
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Differential CCR7 targeting in dendritic cells by three naturally occurring CC-chemokines [PDF]
Frontiers in Immunology, 2016 The CCR7 ligands CCL19 and CCL21 are increasingly recognized as functionally different (biased). Using mature human dendritic cells (DCs), we show that CCL19 is more potent than CCL21 in inducing 3D chemotaxis.
Gertrud Malene Hjortø +8 more
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Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever. [PDF]
PLoS Neglected Tropical Diseases, 2014 The pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear. We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated that the strong ...
Delphine Pannetier +4 more
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Neuronal CC chemokines: the distinct roles of CCL21 and CCL2 in neuropathic pain [PDF]
Frontiers in Cellular Neuroscience, 2014 The development of neuropathic pain in response to peripheral nerve lesion for a large part depends on microglia located at the dorsal horn of the spinal cord.
Knut eBiber, Knut eBiber, Erik eBoddeke
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