Results 91 to 100 of about 13,385 (166)

Serum Hepatocyte Growth Factor Predicts Outcomes in Non‐Acetaminophen Drug‐Induced Acute Liver Failure

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims Regenerative capacity and inflammatory responses are key determinants of outcome in acute liver failure (ALF). However, their prognostic significance in non‐acetaminophen drug‐induced liver injury with acute liver injury or ALF (non‐APAP‐DILI‐ALI/ALF) remains poorly defined.
Tao Wang, Silvia M. Bacot, Kamai Patterson, Devira Friedman, Caroline Taylor, Huixiao Hong, Jie Liu, Mark I. Avigan, Paul Hayashi, Jody A. Rule, William M. Lee, Jorge Rakela, Gerald M. Feldman, Minjun Chen   +13 more
wiley   +1 more source

Pulsed high-dose dexamethasone modulates Th1-/Th2-chemokine imbalance in immune thrombocytopenia

Journal of Translational Medicine, 2016
Background Chemokines and chemokine receptors play important roles in autoimmune diseases; however, their role in immune thrombocytopenia (ITP) is unclear.
Zongtang Liu, Meiying Wang, Shufen Zhou, Ji Ma, Yan Shi, Jun Peng, Ming Hou, Chengshan Guo   +7 more
doaj   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, Volume 16, Issue 10, Page 1094-1106, October 2026.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Inflammatory mediators and dual depression: Potential biomarkers in plasma of primary and substance-induced major depression in cocaine and alcohol use disorders.

PLoS ONE, 2019
Major depressive disorder (MDD) is the most prevalent comorbid mental disorder among people with substance use disorders. The MDD can be both primary and substance-induced and its accurate diagnosis represents a challenge for clinical practice and ...
Nuria García-Marchena, Marta Barrera, Joan Ignasi Mestre-Pintó, Pedro Araos, Antonia Serrano, Clara Pérez-Mañá, Esther Papaseit, Francina Fonseca, Juan Jesús Ruiz, Fernando Rodríguez de Fonseca, Magí Farré, Francisco Javier Pavón, Marta Torrens   +12 more
doaj   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2124-2137, October 2026.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera   +84 more
wiley   +1 more source

Integrative Multiomics Profiling Reveals Immune Determinants of Response to Disitamab Vedotin Plus Penpulimab in HER2‐Low Breast Cancer

MedComm, Volume 7, Issue 10, October 2026.
This prospective single‐arm study evaluated neoadjuvant disitamab vedotin plus penpulimab in 20 patients with Stage II–III HER2‐low breast cancer. The regimen showed preliminary activity (pCR 20.0% intention‐to‐treat, 25.0% evaluable; ORR 56.3%) with manageable toxicity.
Xiaoxiao Liu, Yuting Song, Lei Liu, Aaron Qi Zhang, Xin Xie, Bing Wei, Ping He, Chunying Zhuang, Juanjuan Li, Xi Yan, Tinglun Tian, Xiaorong Zhong, Jie Chen, Yan Cheng, Dan Zheng, Shibao Li, Hao Wang, Ting Luo   +17 more
wiley   +1 more source

Validity of serum CCL11 (Eotaxin-1) and interleukin-13 as prognostic biomarkers in hepatitis C virus induced liver disease

The Egyptian Journal of Internal Medicine
Background Hepatitis C virus (HCV) is the main cause of chronic liver disease (CLD), which affects more than 50 million people around the world. Persistent immune dysregulation promotes hepatocellular damage, fibrotic remodeling and carcinogenesis ...
Nasser Abdallah, Khaled Hussain, Akram Deghady, Samar Raky, Marwa Deif   +4 more
doaj   +1 more source

Piezoelectric Nanofibrous Scaffolds for Promoting the Growth of Spiral Ganglion Neurons via Acoustic Stimulation

Smart Medicine, Volume 5, Issue 5, October 2026.
The piezoelectric nanofibrous scaffolds containing PANI, PLLA and Gelatin exhibited biomimetic structure, components, and piezoelectricity. Benefiting from the oriented nanofibers and electrical stimulation induced by wireless acoustic excitation, the SGNs cultured on the scaffolds showed enhanced neurite alignment, extension, and growth cone ...
Dongyu Xu, Cuntu Cheng, Shan Xu, Chuan Bu, Shuangba He, Sizhe Song, Yu Wang, Busheng Tong, Yangnan Hu, Huan Wang, Renjie Chai   +10 more
wiley   +1 more source

Peripheral chemokine levels in women with recurrent major depression with suicidal ideation Níveis periféricos de quimiocina em mulheres com depressão maior com ideação suicida

Brazilian Journal of Psychiatry, 2012
OBJECTIVE: To compare serum levels of MCP-1/CCL2, RANTES/CCL5, and Eotaxin/CCL11 between female patients with recurrent major depressive disorder (MDD) and healthy controls, verifying if there is a difference in the levels of these mediators between ...
Rodrigo Grassi-Oliveira, Elisa Brieztke, Antônio Teixeira, Júlio Carlos Pezzi, Márcio Zanini, Rodrigo Pestana Lopes, Moisés Evandro Bauer   +6 more
doaj   +1 more source

Genetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response

Molecular Cancer
Nucleic acid vaccines have shown promising potency and efficacy for cancer treatment with robust and specific T-cell responses. Improving the immunogenicity of delivered antigens helps to extend therapeutic efficacy and reduce dose-dependent toxicity ...
Hailong Qi, Zhongjie Sun, Tianle Gao, Yanling Yao, Yu Wang, Weiwei Li, Xudong Wang, Xiaofang Wang, Defang Liu, Jian-Dong Jiang   +9 more
doaj   +1 more source