Results 81 to 90 of about 13,385 (166)

Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling

Immunity & Ageing
Background The chemokine CCL11 is negatively correlated with cognitive function and is able to cause dysfunctions of synaptic plasticity. This research investigate whether CCL11 induce microglia senescence to damage synaptic plasticity and the protective
Sheng Tian, Tianyuan Ye, Chao Tian, Yipeng Zhang, He Li, Hui Shen, Youhua Xu, Xiaorui Cheng   +7 more
doaj   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

The expression of CCL11/eotaxin, CCR3 receptor and eosinophil peroxidase in tumor tissue in gastric and colon cancers

Бюллетень сибирской медицины, 2018
The purpose of the study was to analyze the expression of CCL11/eotaxin, CCR3 receptor to eotaxin and eosinophil peroxidase (EXP) in tumor tissue and its relation to tissue eosinophilia in gastric and colon cancers.Materials and methods. 52 patients with
Yu. V. Kolobovnikova, K. I. Yankovich, E. V. Romanova, A. I. Dmitrieva, V. V. Novitskiy, O. I. Urazova   +5 more
doaj   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Role of CCL11 in eosinophilic lung disease during respiratory syncytial virus infection

, 2005
Respiratory syncytial virus (RSV) is a major viral pathogen of infants and the elderly. Significant morbidity is caused by an overexuberant mixed lung cell infiltrate, which is thought to be driven by chemokines.
Matthews, Stephen P., Tracy Hussell, Peter J. M. Openshaw, Coyle, AJ, Openshaw, Peter J M, Tregoning, JS, Tregoning, John S., Stephen P. Matthews, Hussell, Tracy; id_orcid, Matthews, SP, Hussell, T, John S. Tregoning, Openshaw, PJ, Coyle, Anthony J., Anthony J. Coyle   +14 more
core   +1 more source

Reduced ccl11/eotaxin mediates the beneficial effects of environmental stimulation on the aged hippocampus

, 2021
A deterioration in cognitive performance accompanies brain aging, even in the absence of neurodegenerative pathologies. However, the rate of cognitive decline can be slowed down by enhanced cognitive and sensorimotor stimulation protocols, such as ...
Desiato G., Berardi N., Scabia G., Scali M., Mainardi M., Maffei M., Maffei L., Train the Brain Consortium, Testa G., Del Turco S., Sale A., Matteoli M.   +11 more
core   +1 more source

Analyzing the biological mechanisms of CCL11 in cognitive impairments following COVID-19 infection and populations at greater risk

, 2023
 “Brain fog”, an informal term that encapsulates various neurological symptoms including impaired attention, concentration, speed of information processing, memory, and executive functions, is a persistent symptom common among a quarter of COVID-19 ...
Choi, Jinny
core   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

CCL11 and Effects on Pre-osteoclast Migration

, 2017
Periodontitis is a chronic inflammatory disease due to dental bacteria, and the disease is highly prevalent worldwide. Both environmental factors and genetic variation are confounding factors.
Lång, Johanna
core   +2 more sources