Results 21 to 30 of about 13,385 (166)

Characterization of Cytokines in Donkey Follicular Fluid and Seminal Plasma: A Pilot Study. [PDF]

Reprod Domest Anim
ABSTRACT Post‐breeding endometrial inflammation is a well‐known physiological response in jennies, especially after artificial insemination with frozen–thawed sperm. Bioactive molecules present in reproductive fluids, including cytokines, may contribute to regulating these immune processes. The aim of this study was to characterize the cytokine profile
Company S, Catalán J, Padilla L, Maside C, Miró J, Yeste M.   +5 more
europepmc   +2 more sources

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Pillai JA, Zhu A, Ma C, Wang M, Yang Y, Bekris LM, Khrestian M, DiFilippo FP, Nasrallah M, Burberry A, Leverenz JB, Hou Y, Cheng F, Rao SM.   +13 more
europepmc   +2 more sources

IL-4 Modulates CCL11 and CCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells [PDF]

Cellular Physiology and Biochemistry, 2016
Background/Aims: IL-4 is a multifunctional cytokine that is related with the pathological conditions of periodontal disease. However, it is uncertain whether IL-4 could control T cells migration in periodontal lesions.
Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Takashi Matsuo   +4 more
doaj   +4 more sources

Expression of Ccl11 associates with immune response modulation and protection against neuroinflammation in rats. [PDF]

PLoS ONE, 2012
Multiple sclerosis (MS) is a polygenic disease characterized by inflammation and demyelination in the central nervous system (CNS), which can be modeled in experimental autoimmune encephalomyelitis (EAE).
Milena Z Adzemovic, Johan Öckinger, Manuel Zeitelhofer, Sonja Hochmeister, Amennai Daniel Beyeen, Atul Paulson, Alan Gillett, Melanie Thessen Hedreul, Ruxandra Covacu, Hans Lassmann, Tomas Olsson, Maja Jagodic   +11 more
doaj   +2 more sources

Eosinophils in Colorectal Neoplasms Associated with Expression of CCL11 and CCL24 [PDF]

Journal of Pathology and Translational Medicine, 2016
Background: A decrease in the number of tissue eosinophils is known to reflect the malignancy potential of neoplastic lesions and even prognosis. Increased levels of the chemokines CCL11 and CCL24 in serum and tissue are also known to have diagnostic ...
Hyuck Cho, Sung-Jig Lim, Kyu Yeoun Won, Go Eun Bae, Gou Young Kim, Ji Won Min, Byeong-joo Noh   +6 more
doaj   +2 more sources

Evasins: Biology and Therapeutic Potential of Broad-Spectrum Chemokine Inhibitors. [PDF]

Basic Clin Pharmacol Toxicol
ABSTRACT Ticks are haematophagous parasites that rely on uninterrupted bloodmeals for survival and need an effective strategy to suppress the host inflammatory response. Leukocyte recruitment is a chemokine‐mediated hallmark of inflammation, which ticks counteract via anti‐chemokine proteins in their saliva named evasins.
Bialek EL, Buds R, Dijkgraaf I, Marques PE.   +3 more
europepmc   +2 more sources

Analiza stężeń eotaksyny 1/CCL11, eotaksyny 2/CCL24 i eotaksyny 3/CCL26 w surowicy dorosłych chorych na atopowe zapalenie skóry

Przegląd Dermatologiczny, 2011
Introduction. Eosinophils play an important role in development ofallergic diseases. Recent studies indicate their many relevant functionsin the development of allergic inflammation related to both an effectorand immunomodulatory role. The recognition of
Agnieszka Nawrocka, Tomasz Targowski, Elwira Beata Paluchowska, Witold Owczarek   +3 more
doaj   +1 more source

Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™

Biomolecules, 2013
Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma.
Julie A. Leary
exaly   +3 more sources

CCL11 released by GSDMD-mediated macrophage pyroptosis regulates angiogenesis after hindlimb ischemia

Cell Death Discovery
Peripheral vascular disease (PVD) is an emerging public health burden with a high rate of disability and mortality. Gasdermin D (GSDMD) has been reported to exert pyroptosis and play a critical role in the pathophysiology of many cardiovascular diseases.
Yiwen Wang, Yang Gao, Huairui Shi, Rifeng Gao, Ji’e Yang, Ya’nan Qu, Shiyu Hu, Jian Zhang, Jingpu Wang, Jiatian Cao, Feng Zhang, Junbo Ge   +11 more
doaj   +2 more sources

Brexanolone infusion produces sustained anti-inflammatory and neurotrophic effects in patients with postpartum depression that predict symptom improvement [PDF]

Translational Psychiatry
Postpartum depression (PPD) is linked to neuroimmune dysregulation. Brexanolone, an intravenous formulation of the neurosteroid allopregnanolone and the first FDA-approved treatment for PPD, produces rapid and sustained antidepressant effects.
Irina Balan, Cecilia Isabel Sousa Pearson, Holly Krohn, Todd K. O’Buckley, Kai Xia, Samantha Meltzer-Brody, A. Leslie Morrow, Riah Patterson   +7 more
doaj   +2 more sources