Results 41 to 50 of about 13,385 (166)

CCL11 (Eotaxin) Promotes the Advancement of Aging-Related Cardiovascular Diseases

open access: yesReviews in Cardiovascular Medicine
Aging-related diseases, such as cardiovascular diseases (CVDs), neurodegeneration, cancer, etc., have become important factors that threaten the lifespans of older individuals. A chronic inflammatory response is closely related to aging-related diseases.
Tanwei Zhang   +4 more
doaj   +1 more source

CD14+CD33+ myeloid cell-CCL11-eosinophil signature in ulcerative colitis

open access: yes, 2013
This study tested the hypothesis that eotaxins (CCL11, CCL24, and CCL26) and IL-5 contribute to eosinophil recruitment to the intestine in UC and that intestinal macrophages are important producers of CCL11 in this disease.
Marie Carlson   +9 more
core   +1 more source

Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND:Thymic stromal lymphoproetin (TSLP) is a cytokine secreted by the airway epithelium in response to respiratory viruses and it is known to promote allergic Th2 responses in asthma.
Gustavo Nino   +10 more
doaj   +1 more source

Expression of wild type and variant (Ala23Thr) CCL11.

open access: yes, 2018
Plasmids encoding the genes for wild type and variant (Ala23Thr) CCL11 were expressed in HEK cells and the expression levels determined by (A) EIA (triplicates; ***, pB) Coomassie Blue staining (triplicates).
Susan L. Neuhausen (238692)   +10 more
core   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

The chemokines CCL11, CCL20, CCL21, and CCL24 are preferentially expressed in polarized human secondary lymphoid follicles

open access: yes, 2004
Chemokines regulate cellular trafficking to and from lymphoid follicles. Here, the distribution pattern of four CCL chemokines is defined by in situ hybridization in human lymphoid follicles from tonsils and lymph nodes (LNs) of newborns and adults ...
Müller, Christoph   +4 more
core   +1 more source

Comprehensive analysis of chemokine gene polymorphisms in Korean children with autoimmune thyroid disease

open access: yesScientific Reports, 2023
Chemokines are chemotactic cytokines that can cause directed migration of leukocytes. The aim of this study was to examine differences in single nucleotide polymorphisms (SNP) of chemokine in AITD patients compared to normal controls.
Chungwoo Shin   +4 more
doaj   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

open access: yesAdvanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu   +15 more
wiley   +1 more source

CCL11 and CCR3 protein levels in the inguinal lymph nodes.

open access: yes, 2012
(A) Western blot analysis of CCL11 and its main receptor CCR3 in inguinal lymph nodes on day 7 p.i. Protein levels of both targets were increased in the congenic animals compared to the controls (data normalized to β- actin).
Johan Öckinger (150935)   +11 more
core   +1 more source

Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population

open access: yesJournal of Neuroinflammation, 2012
Background Inflammatory mechanisms are important in stroke risk, and genetic variations in components of the inflammatory response have been implicated as risk factors for stroke.
Zhao Nan   +11 more
doaj   +1 more source

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