Results 121 to 130 of about 94,786 (284)

Mechanism of the Photodecomposition of Stable Triarylmethyl Radicals

open access: yesAngewandte Chemie, EarlyView.
Photolysis of luminescent chlorinated trityl radicals was studied with density functional theory and the decomposition products were isolated and characterized. It proceeds by a 5‐electron electrocyclization then a 1,8‐sigmatropic chloride shift, forming non‐emissive, less stable fluorenyl radicals.
Hannah E. Hackney   +3 more
wiley   +2 more sources

Effect of ethanol extract of leaf of Cajanus indicus spreng in carbon tetrachloride induced hepatopathy in rates in relation to free radical scavenging action

open access: yesJournal of Nobel Medical College, 2012
Phytochemicals, that is, chemicals present in various plants and herbs , are now becoming important candidates for development of drugs.Wide range of medicinals plants {Plants from which potential photochemicals are isolated for development of drugs for ...
Biswajit Majumdar   +2 more
doaj   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

open access: yesAdvanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo   +5 more
wiley   +1 more source

Hepatoprotective activity of Silver Nanoparticles synthesized using aqueous leaf extract of Punica granatum against induced hepatotoxicity in rats

open access: yesیافته‌های نوین در علوم زیستی, 2021
Punica granatum leaf extracts have been used since time immemorial in traditional medicines. It is used for its antioxidant properties. Green nanoparticle synthesis is an emerging field which has opened an entirely different scope for medicinal ...
Manoj Kumar   +6 more
doaj  

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu   +8 more
wiley   +1 more source

Phytolacca dodecandra (Phytolaccaceae) Root Extract Exhibits Antioxidant and Hepatoprotective Activities in Mice with CCl4-Induced Acute Liver Damage

open access: yesClinical and Experimental Gastroenterology, 2021
Birhanu Geta Meharie,1 Tewodros Agedew Tunta2 1Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia; 2Department of Pharmacy, College of Medicine and Health Sciences, Arba Minch University, Arba Minch ...
Meharie BG, Tunta TA
doaj  

Measurement of Trace I-129 Concentrations in CsI Powder and Organic Liquid Scintillator with Accelerator Mass Spectrometry

open access: yes, 2005
Levels of trace radiopurity in active detector materials is a subject of major concern in low-background experiments. Procedures were devised to measure trace concentrations of I-129 in the inorganic salt CsI as well as in organic liquid scintillator ...
Alimonti   +43 more
core   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

open access: yesAdvanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu   +8 more
wiley   +1 more source

Levisticum officinale extract protects against CCl4-induced hepatotoxicity through anti-inflammatory, anti-fibrotic, and antioxidant properties in rats

open access: yesAsian Pacific Journal of Tropical Biomedicine
Objective: To investigate the hepatoprotective effects of Levisticum officinale extract on CCl4-induced hepatotoxicity. Methods: Different doses of Levisticum officinale extract were given orally to rats for 10 days, then rats received a single dose of ...
Nahid Ghaedi   +3 more
doaj   +1 more source

PENGARUH DOSIS DAN FREKUENSI PEMBERIAN FILTRAT BIJI BUNGA MATAHARI (Helianthus annuus L.) TERHADAP KADAR BILIRUBIN TOTAL SERUM PADA TIKUS PUTIH (Rattus norvegicus) YANG DIINDUKSI DENGAN CCl4 [PDF]

open access: yes, 2007
Hepar merupakan organ yang memiliki fungsi: (1) fungsi vaskuler, (2) fungsi ekskretorik, (3) fungsi metabolik dan (4) fungsi protektor. Kerusakan hepar yang terjadi dapat meliputi kerusakan struktur maupun gangguan fungsi hati.
RAHMAWATI, PUTRI
core  

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