Results 161 to 170 of about 37,429 (252)

Managing Autofluorescence in Spectral Flow Cytometry for Macrophage Identification in the Liver

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Autofluorescence in liver tissue is heterogeneous and dynamically altered during metabolic liver disease, complicating spectral flow cytometry analysis. We provide a structured framework for identifying and handling condition‐dependent autofluorescence, demonstrating that inadequate autofluorescence correction biases macrophage quantification and ...
Sabine Daemen, Tuneille I. Adelaar, Panos Barlampas, Xiaodi Zhang, Casper G. Schalkwijk, Kristiaan Wouters   +5 more
wiley   +1 more source

Bile acid retention in efferocytic macrophages shapes their inflammatory status during cholangitis. [PDF]

J Exp Med
Al Jawazneh A, Liebold I, Leyk S, Lanzloth C, Brackrock V, López-López T, Graute S, Aranda-Pardos I, Hamley M, Bahn J, Heeren J, Von Felden J, Lohse AW, Schramm C, Schwinge D, Sáez PJ, A-Gonzalez N, Huber S, Jacobs T, Adlung L, Worthmann A, Bosurgi L.   +21 more
europepmc   +1 more source

Mesenteric Adipose Tissue as a Modulator of Intestinal Inflammation: Mechanistic Insights and Model Systems in Crohn's Disease

European Journal of Immunology, Volume 56, Issue 6, June 2026.
This review explores how mesenteric adipose tissue, particularly creeping fat, contributes to intestinal inflammation through dysregulated adipokine signalling. We explore how metabolic stress alters immune‐adipose interactions and promotes disease progression.
Toka Omar, Carl Weidinger, Britta Siegmund   +2 more
wiley   +1 more source

Artemisinin-Related Therapeutic Strategies for Autoimmune Thyroiditis: Chemokine-Receptor Networks, Spatial Thyroid Biology, and Molecular Mechanisms. [PDF]

Drug Des Devel Ther
Sun Y, Yang X, Zhu Q, Yang R.
europepmc   +1 more source

Inflammatory macrophage-derived plasminogen activator inhibitor-1 exacerbates inflammation through efferocytosis inhibition. [PDF]

Cell Death Discov
Ibrahim AA, Miura H, Terada T, Kawarada M, Watanabe N, Hosokawa H, Ohtsuka M, Miyata T, Yahata T.   +8 more
europepmc   +1 more source

DAMP Laden Extracellular Vesicles From the Airways of Patients With Severe SARS‐CoV‐2 Respiratory Infection Compromise Inflammation and Cellular Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Extracellular vesicles from severe COVID‐19 airways carry depleted miRNAs and elevated DAMPs, reprogramming monocytes toward senescence, impaired metabolism, and predominantly reduced cytokine responses. However, they drive excess IL‐8 production, amplifying neutrophil recruitment and dysfunctional inflammation across the respiratory tract.
April Rees, Oliver Richards, Molly E Raikes, Megan Chambers, Sophie G Reed, Ceri Battle, Hannah Toghill, Luke Newey, Tyler J Joseph, Haiyan An, Hui Zhang, Iain Perry, Jason Webber, Nicholas Jones, Catherine A Thornton   +14 more
wiley   +1 more source

Pathogenic GM-CSF drives functional diversification of inflammatory macrophages in autoimmune arthritis. [PDF]

Sci Adv
Mukoyama H, Takeuchi Y, Ohara D, Lee Y, Watanabe H, Kato H, Kondoh G, Morinobu A, Hirota K.   +8 more
europepmc   +1 more source

Olink Proteomics Reveals CCL2 Aggravates Perihematomal Edema After Intracerebral Hemorrhage in High-Altitude Migrants Via CCR2/NF-κB-Mediated Blood-Brain Barrier Disruption. [PDF]

CNS Neurosci Ther
Huang R, Gao L, Dai Y, Li S, Guru J, Li M, Chen YJ, Wu B, Ru X, Gong Q, Tang J, Zhu G, Chen Y.   +12 more
europepmc   +1 more source

Fluid sparing effects of chemokine (C-C motif) receptor 1 and 2 antagonists during resuscitation from hemorrhagic shock in rat models. [PDF]

PLoS One
Cook EA, Ogunsina O, Gao X, Majetschak M.   +3 more
europepmc   +1 more source

Corrigendum to: Targeting the CCL2–CCR2 axis for atheroprotection

European Heart Journal, 2022
openaire   +2 more sources