Results 61 to 70 of about 22,866 (205)

Repositioning Non‐Ablative Fractional Lasers ‐ Molecular and Histological Insights from a scoping review

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Near‐infrared non‐ablative fractional lasers (NAFL) are established for skin rejuvenation and scar treatment and have attracted interest for their expanding therapeutic potential. This scoping review aims to revisit and reposition NAFL within a fluence‐dependent continuum of tissue modulation, based on evidence from 27 studies of lasers ...
Guy Erlich, Uwe Paasch, Kevin Jacobsen, Merete Haedersdal, Uffe Høgh Olesen   +4 more
wiley   +1 more source

Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective

Periodontology 2000, EarlyView.
Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh, Andrea Mombelli, Frank Schwarz, Jan Derks   +3 more
wiley   +1 more source

C-C CHEMOKINE RECEPTOR TYPE 3 INHIBITORS: BIOACTIVITY PREDICTION USING LOCAL VERTEX INVARIANTS BASED ON THERMAL CONDUCTIVITY LAYER MATRIX

Studia Universitatis Babes-Bolyai Chemia, 2018
A series of compounds with known inhibitory activity for C-C chemokine receptor type 3 (CCR3) was considered in order to build a predictive model useful in further development of novel CCR3 inhibitors. Model was built using topological descriptors (Cluj
Claudiu N. LUNGU
doaj   +1 more source

Bone Marrow Failure Model Mimics Aplastic Anemia Patients: Single‐Cell Landscape of Immune Response Reveals Novel Mechanisms of Immune Imbalance in AA

Cancer Medicine, Volume 15, Issue 6, June 2026.
Single‐cell RNA‐seq is used in a mouse model of immune‐mediated bone marrow failure. Approach to platelets and mitochondrial data. Analysis of various immune cell landscapes, interactions and driving factors in BMF, involving platelets, CD4+ T Cells, CD8+ T Cells, macrophages, and mitochondrial energy metabolism pathways.
Shuai Tan, Fang Fang, Jing Sun, Yumeng Li, Yaochi Chen, Wanling Sun   +5 more
wiley   +1 more source

Tryptase-Chymase Double-Positive Human Mast Cells Express the Eotaxin Receptor CCR3 and Are Attracted by CCR3-Binding Chemokines [PDF]

The American Journal of Pathology, 1999
Eosinophils, basophils, and Th2 cells express the chemokine receptor CCR3, which binds eotaxin, RANTES, and some other chemokines. Using immunohistochemistry and flow cytometry, we demonstrate that CCR3 is also expressed by a variable proportion of human mast cells in gut, skin, and lung tissue.
ROMAGNANI, PAOLA, A. DE PAOLIS, C. BELTRAME, ANNUNZIATO, FRANCESCO, V. DENTE, MAGGI, ENRICO, ROMAGNANI, SERGIO, G. MARONE   +7 more
openaire   +5 more sources

Artificial Sweeteners and Autoimmune Diseases: Insights From Integrative Bioinformatics and Mendelian Randomization

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study provides a novel molecular perspective on the role of AS in ADs development. We identified a positive association between artificially sweetened cereal intake and ADs risk and revealed multiple pathogenic mechanisms involving apoptosis, inflammatory signaling, immune activation, and gut microbiota dysbiosis.
Yupei Liu, Jizhen Huang, Xue Hu, Shan Tian, Jiao Li, Shiyun Tan, Weiguo Dong   +6 more
wiley   +1 more source

High Radiological Severity in CRSwNP Is Associated With a Mixed Type 2/Type 3 Epithelial Inflammatory Signature

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
This study demonstrates that high radiological severity in patients with CRSwNP is uniquely characterized by a mixed Type 2 and Type 3 epithelial inflammatory signature. These findings suggest that severe disease involves a complex immune endotype, providing new insights into precision therapeutic strategies for refractory CRSwNP.
Guangfu Xu, Ming Tian, Kanghua Wang, Yunping Fan, Yueqi Sun, Chang Liu   +5 more
wiley   +1 more source

Functional expression of the eotaxin receptor CCR3 in CD30+ cutaneous T-cell lymphoma

, 2003
Little is known about mechanisms involved in skin-specific homing of cutaneous T-cell lymphoma (CTCL). Chemokine/chemokine receptor interactions have been implicated in the homing of lymphoma cells to various tissue sites.
Martin Kleinhans, Reinhard Dummer, Günter Burg, Gilliet, M, Dummer, R, Michel Gilliet, Kadin, M E, Marshall E. Kadin, Burg, G, Nestle, F O, Kleinhans, M, Frank O. Nestle, Tun-Kyi, A, Adrian Tun-Kyi   +13 more
core   +1 more source

CCR3 deficiency is associated with increased osteoclast activity and reduced cortical bone volume in adult male mice

, 2021
Increasing evidence emphasizes the importance of chemokines and chemokine receptors as regulators of bone remodeling. The C–C chemokine receptor 3 (CCR3) is dramatically upregulated during osteoclastogenesis, but the role of CCR3 in osteoclast formation ...
Lundberg, Pernilla, Kindstedt, Elin,, Eklund, Michaela, Johansson, Marcus J. O.,, Sulniute, Rima, Holm, Cecilia Koskinen, Lindquist, Susanne,, Eklund, Michaela,, Lundberg, Pernilla,, Rosendahl, Sara, Lindquist, Susanne, Johansson, Marcus J. O., Kindstedt, Elin, Sulniute, Rima,, Holm, Cecilia Koskinen,, Rosendahl, Sara,   +15 more
core   +1 more source

Investigation into imbalance of Th1/Th2 cells in cirrhotic, hypersplenic rats

Journal of International Medical Research, 2020
Objectives To evaluate the Th1/Th2 cell profile in spleens of cirrhotic and hypersplenic rats by investigating the expression of Th1-associated chemokine receptors CXCR3, CCR5 and Th2-associated chemokine receptor CCR3.
Yunfu Lv, Yejuan Li, Ning Liu, Yonghong Dong, Jie Deng   +4 more
doaj   +1 more source