Results 71 to 80 of about 22,866 (205)
Single‐Cell Omics Analysis of Human Basophils Reveals Two Transcriptionally Distinct Populations
Integrated single‐cell transcriptomics and large‐scale immunophenotyping reveal the molecular landscape of human basophils. Circulating basophils comprise two transcriptionally distinct populations. A user‐friendly web resource enables interactive exploration of the generated data.
Sofia Papavasileiou +13 more
wiley +1 more source
Role of CCR3 in aging rhesus monkey brain [PDF]
Each year, aging and age-related deficits in cognitive function affect larger population worldwide. Research on aging has focused on changes in gray matter and white matter with age.
Bu, Yi
core
Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets
Platelets are known to contain platelet factor 4 and beta-thromboglobulin, alpha-chemokines containing the CXC motif, but recent studies extended the range to the beta-family characterized by the CC motif, including RANTES and Gro-alpha.
Christine A. Power +11 more
core +1 more source
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Adrian P. Mansini +10 more
wiley +1 more source
Studies of the human CCR3 chemokine receptor: development of a cell line stably expressing CCR3, receptor purification and characterization, and phosphopeptide enrichment methods to study the CCR3 GPCR signaling pathway [PDF]
Studies of the human CCR3 chemokine receptor: development of a cell line stably expressing CCR3, receptor purification and characterization by mass spectrometry, and phosphoproteomic methods to study the CCR3 GPCR signaling pathway.
NC DOCKS at The University of North Carolina at Greensboro +1 more
core
From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology
ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki +2 more
wiley +1 more source
<b><i>Purpose:</i></b> To investigate the association between retinal neovascularization and the CC chemokine receptor-3 (CCR3) in a mouse model of oxygen-induced retinopathy (OIR).
Yuichiro Ogura +5 more
core +1 more source
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu +15 more
wiley +1 more source
CCR3 is expressed in the retina and at CNV lesions, and upregulated in laser-treated retina.
(A) Immunolabeling of CCR3 in retinal cryosections from non-lasered mice without injection (Non-lasered/Non-injected) and from mice 7 days after laser without injection (Lasered/Non-injected) mice (Mag, 20X; Scale bar, 50 μm; Green, CCR3; Blue, DAPI; Red,
Deeksha Gambhir (2839451) +6 more
core +1 more source
The pathogenesis of allergic asthma is similar to that of allergic rhinitis, with inflammation cells producing and releasing inflammatory mediators and cytokines closely related to CCR3.Based on the theory of "one airway, one disease", the use of CCR3 ...
Youwei Bao +12 more
doaj +1 more source

