Results 71 to 80 of about 22,866 (205)

Single‐Cell Omics Analysis of Human Basophils Reveals Two Transcriptionally Distinct Populations

open access: yesAllergy, Volume 81, Issue 6, Page 2059-2068, June 2026.
Integrated single‐cell transcriptomics and large‐scale immunophenotyping reveal the molecular landscape of human basophils. Circulating basophils comprise two transcriptionally distinct populations. A user‐friendly web resource enables interactive exploration of the generated data.
Sofia Papavasileiou   +13 more
wiley   +1 more source

Role of CCR3 in aging rhesus monkey brain [PDF]

open access: yes, 2019
Each year, aging and age-related deficits in cognitive function affect larger population worldwide. Research on aging has focused on changes in gray matter and white matter with age.
Bu, Yi
core  

Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets

open access: yes, 2000
Platelets are known to contain platelet factor 4 and beta-thromboglobulin, alpha-chemokines containing the CXC motif, but recent studies extended the range to the beta-family characterized by the CC motif, including RANTES and Gro-alpha.
Christine A. Power   +11 more
core   +1 more source

The Secretome of Bullous Pemphigoid IgG‐Treated Keratinocytes Induces a Pro‐Inflammatory Eosinophil Response

open access: yesExperimental Dermatology, Volume 35, Issue 5, May 2026.
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease whereby the cutaneous antigens BP180 and BP230 are targeted by autoantibodies. Skin lesions in BP are characterized by an abundance of eosinophils. We recently demonstrated that the treatment of keratinocytes with antibodies from patients with BP induces a robust inflammatory response
Adrian P. Mansini   +10 more
wiley   +1 more source

Studies of the human CCR3 chemokine receptor: development of a cell line stably expressing CCR3, receptor purification and characterization, and phosphopeptide enrichment methods to study the CCR3 GPCR signaling pathway [PDF]

open access: yes, 2016
Studies of the human CCR3 chemokine receptor: development of a cell line stably expressing CCR3, receptor purification and characterization by mass spectrometry, and phosphoproteomic methods to study the CCR3 GPCR signaling pathway.
NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology

open access: yesImmunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki   +2 more
wiley   +1 more source

Suppression of Retinal Neovascularization by Anti-CCR3 Treatment in an Oxygen-Induced Retinopathy Model in Mice

open access: yes, 2017
<b><i>Purpose:</i></b> To investigate the association between retinal neovascularization and the CC chemokine receptor-3 (CCR3) in a mouse model of oxygen-induced retinopathy (OIR).
Yuichiro Ogura   +5 more
core   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu   +15 more
wiley   +1 more source

CCR3 is expressed in the retina and at CNV lesions, and upregulated in laser-treated retina.

open access: yes, 2016
(A) Immunolabeling of CCR3 in retinal cryosections from non-lasered mice without injection (Non-lasered/Non-injected) and from mice 7 days after laser without injection (Lasered/Non-injected) mice (Mag, 20X; Scale bar, 50 μm; Green, CCR3; Blue, DAPI; Red,
Deeksha Gambhir (2839451)   +6 more
core   +1 more source

The study of the role of purified anti-mouse CD193 (CCR3) antibody in allergic rhinitis mouse animal models

open access: yesScientific Reports
The pathogenesis of allergic asthma is similar to that of allergic rhinitis, with inflammation cells producing and releasing inflammatory mediators and cytokines closely related to CCR3.Based on the theory of "one airway, one disease", the use of CCR3 ...
Youwei Bao   +12 more
doaj   +1 more source

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