Results 131 to 140 of about 82,628 (226)

Sex‐Specific Factors Influencing HIV Infection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

Sex Differences in Cancer Immunotherapy—Clinical Evidence and Mechanisms With a Focus on NSCLC

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Accumulating evidence suggests that the immune system shows subtle but relevant differences between men and women. These differences may have an impact on cancer development and TME composition as well as responses to and adverse events elicited by immunotherapies.
Eva Krieghoff‐Henning, Balagopal Pai, Maike Collienne, Isabel Ben‐Batalla, Sonja Loges   +4 more
wiley   +1 more source

Routine use of a spike‐in DNA in‐process control for foetal RHD genotyping: Testing the real‐world effectiveness of this ‘canary’

Vox Sanguinis, Volume 121, Issue 3, Page 361-369, March 2026.
Abstract Background and Objectives Non‐invasive foetal RHD (fRHD) genotyping is widely implemented to prevent unnecessary administration of antenatal anti‐D prophylaxis. Reliable assay performance is critical. In line with expert recommendations, we validated and implemented an artificial spike‐in extraction control in our previously published assay ...
Renske M. van ’t Oever, Heleen Woortmeijer, Ahmad Javadi, Aicha Ait Soussan, Barbera Veldhuisen, Claudia C. Folman, C. Ellen van der Schoot, Erik H. van Beers, Masja de Haas   +8 more
wiley   +1 more source

Gpr75 Deletion in Adipocytes Protects From Diet‐Induced Obesity: Changes in Glucose Homeostasis and Inflammatory Responses

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
Diet‐driven weight gain exhibited sex differences; weight gain of adipocyte‐deficient Gpr75 (adipo‐Gpr75−/−) female mice was greatly attenuated compared to wild‐type (adipo‐Gpr75+/+) mice, whereas male adipo Gpr75−/− mice gained weight similar to wild type. Nevertheless, compared to wild‐type adipo‐Gpr75+/+ mice, which showed all the characteristics of
Sakib Hossain, Elizabeth Villegas, Catherine Liapes, Nahid Sultana, Dorina Krasniqi, Danielle Diegisser, Ana Castro, Comfort Williams, Artiom Gruzdev, Darryl C. Zeldin, Victor Garcia, Michal Laniado Schwartzman   +11 more
wiley   +1 more source

Seeing CCR5 [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions.

PLoS Pathogens
Cytolytic CD8+ T cells mediate immunopathology in cutaneous leishmaniasis without controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion that could be targeted to ameliorate disease severity.
Laís Amorim Sacramento, Camila Farias Amorim, Claudia G Lombana, Daniel Beiting, Fernanda Novais, Lucas P Carvalho, Edgar M Carvalho, Phillip Scott   +7 more
doaj   +1 more source

CCR5 Gene [PDF]

, 2020
openaire   +1 more source

Renal allograft rejection in chemokine receptor Ccr1-/-, Ccr5-/- and Ccr1-/-/Ccr5-/- mice and impact of Ccr5 deficiency on macrophage polarization

, 2009
Previous studies showed that loss of the chemokine receptor Ccr1 or Ccr5 has a beneficial effect on survival of cardiac, carotid, corneal and islet allografts in mice. Additionally, human renal allograft recipients homozygous for a null allele of CCR5 (CCR5delta32) experience significantly prolonged allograft survival.
openaire   +2 more sources

CCR5 gene editing – Revisiting pros and cons of CCR5 absence

Infection, Genetics and Evolution, 2019
Joel Henrique Ellwanger, Valéria de Lima Kaminski, José Artur Bogo Chies   +2 more
openaire   +2 more sources

Astrocytic CCL5 orchestrates CCR5-positive neuronal necroptosis in subarachnoid hemorrhage. [PDF]

J Neuroinflammation
Chen P, Jiang YH, Xue SQ, Wang Y, Lin WL, Shi MY, Li SJ, Sun WW, Zhao JX, Kang DZ, Ye ZC, Lin QS.   +11 more
europepmc   +1 more source