Results 31 to 40 of about 57,461 (287)

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis [PDF]

, 2017
Background: Dysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied.
Alessandro, Riccardo, Ciccia, Francesco, Cypers, Heleen, Di Benedetto, Paola, Elewaut, Dirk, Fasano, Alessio, Gabrielli, Armando, Guggino, Giuliana, Luchetti, Michele Maria, Milling, Simon, Rizzo, Aroldo, Saieva, Laura, Stampone, Tommaso, Triolo, Giovanni   +13 more
core   +2 more sources

CD163: A Specific Marker of Macrophages in Paraffin-Embedded Tissue Samples [PDF]

American Journal of Clinical Pathology, 2004
Paraffin-section immunohistochemical analysis was performed using a monoclonal antibody against CD163 to evaluate the antibody's usefulness in identifying cells of monocyte/macrophage lineage in normal and neoplastic conditions. Normal human tissue samples and samples from 211 hematopoietic disorders and 115 nonhematopoietic neoplasms were examined ...
Sean K, Lau, Peiguo G, Chu, Lawrence M, Weiss   +2 more
openaire   +2 more sources

Platelets promote macrophage polarization toward pro-inflammatory phenotype and increase survival of septic mice [PDF]

, 2019
We investigated the contribution of human platelets to macrophage effector properties in the presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for platelet transfusion in septic animals.
Carestia, Agostina, Carrera Silva, Eugenio Antonio, Errasti, Andrea Emilse, Gomez, Ricardo Martin, Jenne, Craig N., Mena, Hebe Agustina, Negrotto, Soledad, Olexen, Cinthia Mariel, Ortiz Wilczyñski, Juan Manuel, Schattner, Mirta Ana   +9 more
core   +1 more source

Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virus

Journal of Integrative Agriculture, 2023
Porcine reproductive and respiratory syndrome (PRRS) is recognized as one of the most infectious viral diseases of swine. Although Cluster of differentiation 163 (CD163) is identified as an essential receptor for mediating PRRS virus (PRRSV) infection ...
Kui XU, Yan-rong ZHOU, Hai-tao SHANG, Chang-jiang XU, Ran TAO, Wan-jun HAO, Sha-sha LIU, Yu-lian MU, Shao-bo XIAO, Kui LI   +9 more
doaj   +1 more source

Urinary Soluble CD163 in Active Renal Vasculitis [PDF]

Journal of the American Society of Nephrology, 2016
A specific biomarker that can separate active renal vasculitis from other causes of renal dysfunction is lacking, with a kidney biopsy often being required. Soluble CD163 (sCD163), shed by monocytes and macrophages, has been reported as a potential biomarker in diseases associated with excessive macrophage activation. Thus, we hypothesized that urinary
O'Reilly, Vincent P., Wong, Limy, Kennedy, Claire, Elliott, Louise A., O'Meachair, Shane, Coughlan, Alice Marie, O'Brien, Eoin C., Ryan, Michelle M., Sandoval, Diego, Connolly, Emma, Dekkema, Gerjan J., Lau, Jiaying, Abdulahad, Wayel H., Heeringa, Peter, Buckley, Colm, O'Brien, Cathal, Finn, Stephen, Cohen, Clemens D., Lindemeyer, Maja T., Hickey, Fionnuala B., O'Hara, Paul V., Feighery, Conleth, Moran, Sarah M., Mellotte, George, Clarkson, Michael R., Dorman, Anthony J., Murray, Patrick T., Little, Mark A., Sanders, Johannes   +28 more
openaire   +2 more sources

RNA‐seq and ATAC‐seq analysis of CD163+ macrophage‐induced progestin‐insensitive endometrial cancer cells

Cancer Medicine, 2023
Background Progestins are used as fertility‐sparing regimens for young patients with stage 1A endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH).
Lulu Wang, Qiaoying Lv, Pengfei Wu, Shuhan Luo, Sijia Liu, Xiaojun Chen, Xuezhen Luo   +6 more
doaj   +1 more source

The macrophage scavenger receptor CD163

Immunobiology, 2005
Mature tissue macrophages form a first line of defense to recognize and eliminate potential pathogens; these specialized cells are capable of phagocytosis, degradation of self and foreign materials, establishment of cell-cell interactions, and the production of inflammatory mediators.
Fabriek, Babs O., Dijkstra, Christine D., van den Berg, Timo K.   +2 more
openaire   +3 more sources

Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis [PDF]

Arthritis & Rheumatism, 2004
AbstractObjectiveSince CD163+ macrophages are selectively increased in spondylarthropathy (SpA) synovitis, we investigated the role of CD163+ macrophages in synovial inflammation.MethodsSynovial biopsy samples from 26 SpA and 23 rheumatoid arthritis (RA) patients were analyzed for macrophage and lymphocyte subsets.
Baeten, D., Møller, H.J., Delanghe, J., Veys, E.M., Moestrup, S.K., Keyser, F.De   +5 more
openaire   +3 more sources

KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages [PDF]

, 2016
Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by shifting them toward an anti-inflammatory, pro-tumor phenotype.
Catalano, M, D'Alessandro, G, Di Angelantonio, S, Esposito, V, Esposito, V, Golia, MT, Grimaldi, A, Grössinger, EM, Limatola, C, Ragozzino, D, Santoro, A, Wulff, H   +11 more
core   +2 more sources

Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals. [PDF]

PLoS ONE, 2011
CD163, a haptoglobin-hemoglobin (Hp-Hb) scavenger receptor, expressed by monocytes and macrophages, is important in resolution of inflammation. Age-related non-AIDS co-morbidities in HIV-infected individuals, particularly dementia and cardiovascular ...
Emma Tippett, Wan-Jung Cheng, Clare Westhorpe, Paul U Cameron, Bruce J Brew, Sharon R Lewin, Anthony Jaworowski, Suzanne M Crowe   +7 more
doaj   +1 more source