Results 101 to 110 of about 13,147 (200)
Cancer Medicine, 2019 Background Anaplastic thyroid carcinomas are associated with rapid tumor growth, short survival time and without any promising therapy to improve the poor prognosis.
Florian Weber +6 more
doaj +1 more source
The Pathophysiological Relevance of the iNKT Cell/Mononuclear Phagocyte Crosstalk in Tissues
Frontiers in Immunology, 2018 CD1d-restricted Natural Killer T (NKT) cells are regarded as sentinels of tissue integrity by sensing local cell stress and damage. This occurs via recognition of CD1d-restricted lipid antigens, generated by stress-related metabolic changes, and ...
Filippo Cortesi +4 more
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Human respiratory epithelial cells express CD1d protein.
, 2013 Panel A: Flow cytometry analysis of CD1d expression on Beas2B and A549 epithelial cell lines, using three anti-human CD1d mAbs – clones 42, 51.1.3, and NOR3.2.
Kambez Hajipouran Benam (346292) +3 more
core +1 more source
Expression of six CD1D alternatively spliced CD1D variants in human respiratory epithelial cells.
, 2013 Panel A: Schematic illustration of primer pairs “C/C”, “D/D”, and “D/E” annealing sites on CD1D mRNA, and corresponding full-length product sizes. Panel B: RT-PCR on primary bronchial epithelial cells detected a 305-bp band.
Kambez Hajipouran Benam (346292) +3 more
core +1 more source
Synthesis of a 2ꞌꞌ-Deoxy-β-GalCer
Molecules, 2014 Structural studies of ternary complexes of CD1d/glycosyl ceramides/iNKT cells and CD1d/sulfatide/sulfatide reactive Type II NKT cells have shown how the polar moieties on the glycolipids interact with both the antigen presenting protein (CD1d) and the T ...
Meena S. Thakur +3 more
doaj +1 more source
Complex structure of the Vα24− TCR with CD1d-αGalCer.
, 2013 (A) Left panel, ribbon representation of the human Vα24− TCR J24.N22 (slate, α chain; orange, β chain) in complex with human CD1d-β2m (ribbon, white) and αGalCer (sticks, yellow).
Jenny Gumperz (264372) +4 more
core +1 more source
Cord blood Vα24-Vβ11 natural killer T cells display a Th2-chemokine receptor profile and cytokine responses [PDF]
, 2011 Background: The fetal immune system is characterized by a Th2 bias but it is unclear how the Th2 predominance is established. Natural killer T (NKT) cells are a rare subset of T cells with immune regulatory functions and are already activated in utero ...
Elfriede Noessner +32 more
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Aberrant Presentation of Self-Lipids by Autoimmune B Cells Depletes Peripheral iNKT Cells
Cell Reports, 2014 Summary: Invariant natural killer T (iNKT) cells provide cognate help via CD1d to lipid antigen-presenting B cells for antibody production, but whether B cells reciprocally regulate iNKT cells remains largely unexplored.
Andy Hee-Meng Tan +5 more
doaj +1 more source
Tandem repeats modify the structure of the canine CD1D gene [PDF]
, 2013 Among the CD1 proteins that present lipid antigens to T cells, CD1d is the only one that stimulates a population of T cells with an invariant T-cell receptor known as NKT cells.
Herrmann T. +6 more
core +1 more source