Results 51 to 60 of about 10,329 (179)
MedComm, Volume 7, Issue 8, August 2026.Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang +3 more
wiley +1 more source
Role of CD1d in Coxsackievirus B3-Induced Myocarditis [PDF]
The Journal of Immunology, 2003 Abstract The myocarditic (H3) variant of Coxsackievirus B3 (CVB3) causes severe myocarditis in BALB/c mice and BALB/c mice lacking the invariant Jα281 gene, but minimal disease in BALB/c CD1d−/− animals. This indicates that CD1d expression is important in this disease but does not involve the invariant NKT cell often associated with ...
Huber, Sally +2 more
openaire +3 more sources
Wellcome Open Research, 2019 Background: Lipid antigens are presented on the surface of cells by the CD1 family of glycoproteins, which have structural and functional similarity to MHC class I molecules.
Maria Shamin +3 more
doaj +1 more source
Structural Dynamics of the Lipid Antigen-Binding Site of CD1d Protein
Biomolecules, 2020 CD1 molecules present lipid antigens to T-cells in early stages of immune responses. Whereas CD1‒lipid‒T-cell receptors interactions are reasonably understood, molecular details on initial trafficking and loading of lipids onto CD1 proteins are less ...
Bruno Cuevas-Zuviría +4 more
doaj +1 more source
PLoS Pathogens, 2023 One of the major pathogenesis mechanisms of SARS-CoV-2 is its potent suppression of innate immunity, including blocking the production of type I interferons.
Hongjia Lu +13 more
doaj +1 more source
Machine Learning of Personal Repertoires From Public T Cell Receptors
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT The T‐cell receptor (TCR) repertoire records an individual's immunological history, but most unique CDR3 sequences in any one person are private and uninformative about anyone else. A small subset, however, recurs predictably across unrelated donors.
Or Malca, Alona Zilberberg, Sol Efroni
wiley +1 more source
Cancer Medicine, Volume 15, Issue 7, July 2026.ABSTRACT Background Sialic acid‐binding immunoglobulin‐like lectin 10 (SIGLEC10), a member of the SIGLEC family, is selectively expressed on multiple immune cell subsets and plays a key role in immune regulation through the recognition of sialylated ligands.
Chuang Miao, Fei Qian
wiley +1 more source
Could Fabry Disease Cause Giant Coronary Aneurysms in a 7‐Month‐Old Infant: A Case Report
Clinical Case Reports, Volume 14, Issue 7, July 2026.ABSTRACT Fabry disease is a rare X‐linked lysosomal storage disorder that can affect multiple organs. Cardiac involvement, one of its significant manifestations, can begin in childhood and is more prevalent in males, with severity increasing with age and disease progression.
Reza Shabanian +5 more
wiley +1 more source
CD1d-expressing breast cancer cells modulate NKT cell-mediated antitumor immunity in a murine model of breast cancer metastasis. [PDF]
PLoS ONE, 2011 Tumor tolerance and immune suppression remain formidable obstacles to the efficacy of immunotherapies that harness the immune system to eradicate breast cancer.
Laura M Hix +5 more
doaj +1 more source
Cancer Nexus, Volume 2, Issue 3, July 2026.ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang +4 more
wiley +1 more source