Results 151 to 160 of about 36,599 (239)

Image_4_Significance of CD47 and Its Association With Tumor Immune Microenvironment Heterogeneity in Ovarian Cancer.jpeg

, 2021
Lan Yu (346201), Yi Ding (172783), Ting Wan (7410267), Ting Deng (94081), He Huang (50693), Jihong Liu (147629)   +5 more
openalex   +2 more sources

The glia‐immune network: Astrocytes and oligodendrocytes as microglial co‐ordinators in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend The glia‐immune network involves the communication(s) of glia via immune signalling pathways. In neuro‐homeostasis these pathways have been shown to modulate key processes such as synaptic pruning and myelination. The dynamics of these processes is critical to CNS function.
Verity F. T. Mitchener, Millie J. Thackray, I. Lorena Arancibia‐Cárcamo   +2 more
wiley   +1 more source

Targeting CD47/SIRPα in Acute Myeloid Leukemia and Myelodysplastic Syndrome: Preclinical and Clinical Developments of Magrolimab [PDF]

Journal of Immunotherapy and Precision Oncology, 2021
Fadi Haddad, Naval Daver
doaj   +1 more source

CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

, 2015
Xiaojuan Liu, Yang Pu, Kyle R. Cron, Liufu Deng, Justin Kline, William A. Frazier, Hairong Xu, Hua Peng, Yang–Xin Fu, Meng Xu   +9 more
openalex   +2 more sources

Is CD47 an innate immune checkpoint for tumor evasion? [PDF]

, 2017
Xiaojuan Liu, Hyunwoo Kwon, Zihai Li, Yang-Xin Fu   +3 more
openalex   +1 more source

Data from Natural Killer Cell Recruitment and Activation Are Regulated by CD47 Expression in the Tumor Microenvironment

, 2023
Pulak Ranjan Nath, Dipasmita Pal-Nath, Ajeet Mandal, Margaret C. Cam, Anthony L. Schwartz, David D. Roberts   +5 more
openalex   +1 more source

A Machine Learning‐Optimized Immunogenic Cell Death Signature Reveals Tumor Immunogenicity and the Immunotherapy Response of Pancancer

MedComm – Future Medicine, Volume 4, Issue 4, December 2025.
This study introduces an innovative adversarial validation (AV) strategy integrated with machine learning to mitigate the problem of data set shift and enhance analyses of pan‐cancer immunogenicity. It identifies key immunogenic cell death‐related biomarkers and demonstrates their predictive potential for survival outcomes and responses to PD‐1 ...
Li Qiu, Danqing Huang, Yuening Zhang, Yingying Zhou, Ming Luo, Chengdong Zhang, Ying Huang, Mingyuan Zou, Wenlong Lu, Hui Liu, Shaowei Liu, Haoyang Huang, Kaiwen Ye, Yuan Hui, Cheng Tang, Zilong Yan, Xi Zhong, Zhiguo Luo, Hongxin Huang, Ming Zhou, Guangshuai Jia, Qibin Leng, Jun Liu   +22 more
wiley   +1 more source

The anti‐aging Klotho protects glioblastoma macrophages from radiotherapy‐induced inflammation and predicts immunotherapy response

International Journal of Cancer, Volume 157, Issue 10, Page 2156-2172, 15 November 2025.
What's New? The anti‐aging protein klotho (KL) is a potential tumor suppressor and prognostic marker in glioblastoma. Little is known, however, about its mechanism of action and clinical relevance. This study examined KL expression in the setting of persistent inflammation and other stressors, including radiotherapy.
Andrea Galluzzo, Martina Maffezzini, Maria Luisa Fumagalli, Irene Sambruni, Silvia Musio, Monica Patanè, Rosina Paterra, Erika Salvi, Manuel Facciolla, Micaela Milani, Marco Schiariti, Luca Mattei, Alessandra Rossi, Marica Eoli, Luigi Poliani, Antonio Silvani, Bianca Pollo, Laura Fariselli, Natalia Di Ianni, Serena Pellegatta   +19 more
wiley   +1 more source

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

Advanced Healthcare Materials, Volume 14, Issue 28, November 3, 2025.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng, Aijun Liang, Maximus CF Yeung, Sze Keong Tey, Kam‐Leung Siu, Sin‐Yee Fung, Dong‐Yan Jin, Judy Wai Ping Yam   +7 more
wiley   +1 more source

Clinical Benefits of Combination Immunotherapy Over Standard Immunotherapy Monotherapy in Previously Treated Advanced Esophageal Squamous Cell Carcinoma: A Systematic Review and Meta‐Analysis

Cancer Medicine, Volume 14, Issue 21, November 2025.
ABSTRACT Purpose Programmed cell death protein 1 (PD‐1) inhibitor monotherapy is the standard second‐line treatment for esophageal squamous cell carcinoma (ESCC), but the clinical response and survival outcomes still remain unsatisfactory. This systematic review aims to assess the efficacy and safety of combined immunotherapy strategies in previously ...
Yong Chen, Zixuan Chen, Hong Guo, Heng Zhou, Yizhou Deng, Rui Wang, Fang Han, Haiyan Mao, Zhengrong Zhang, Yunjiang Wu, Ying Li   +10 more
wiley   +1 more source