Results 111 to 120 of about 150,310 (246)

Characteristics, Determinants, and Clinical Relevance of CD4 T Cell Recovery to <500 Cells/µL in HIV Type 1—Infected Individuals Receiving Potent Antiretroviral Therapy [PDF]

, 2017
Background. The CD4 T cell count recovery in human immunodeficiency virus type 1 (HIV-1)—infected individuals receiving potent antiretroviral therapy (ART) shows high variability. We studied the determinants and the clinical relevance of incomplete CD4 T
Battegay, Manuel, Bernasconi, Enos, Cavassini, Matthias, Furrer, Hansjakob, Hirschel, Bernard, Kaufmann, Gilbert R., Ledergerber, Bruno, Opravil, Milos, Perrin, Luc, Rickenbach, Martin, Vernazza, Pietro   +10 more
core  

Causal comparative effectiveness analysis of dynamic continuous-time treatment initiation rules with sparsely measured outcomes and death [PDF]

arXiv, 2019
Evidence supporting the current World Health Organization recommendations of early antiretroviral therapy (ART) initiation for adolescents is inconclusive. We leverage a large observational data and compare, in terms of mortality and CD4 cell count, the dynamic treatment initiation rules for HIV-infected adolescents.
arxiv  

The relationship between the systemic inflammatory response, tumour proliferative activity, T-lymphocytic and macrophage infiltration, microvessel density and survival in patients with primary operable breast cancer [PDF]

, 2008
The significance of the inter-relationship between tumour and host local/systemic inflammatory responses in primary operable invasive breast cancer is limited.
A Ciucci, A Lannigan, A-M McNicol, AHS Lee, AHS Lee, AM Al Murri, AM Al Murri, AM Al Murri, AM McNicol, B Uzzan, C Badoual, C O'Sullivan, C Wilson, CD Griffith, CG Lis, D C McMillan, DC McMillan, DC McMillan, DC McMillan, EJ Bromwich, EY Lin, G Zhang, H Trihia, HM Ogmundsdottir, HO Wintzer, I Laursen, J Bell, J C Doughty, J Galon, J Vakkila, JA Anderson, JA Soreide, JL Yu, K Canna, KV Albuquerque, LM Coussens, LM Forrest, M Hilmy, M Retsky, M Toi, MC Haffner, MP Margarson, N Jonjic, P Goldwasser, P Reizenstein, PA McArdle, RD Leek, S Hansen, S Hansen, S Tsutsui, S Vgenopoulou, SM Pupa, SM Veronese, T Scholzen, TH Stewart, V Carstairs, Y Zhou   +56 more
core   +2 more sources

Recurring Candida albicans esophagitis in a HIV-infected patient undergoing long-Term antiretroviral therapy, and with absent-negligible immunodeficiency

Brazilian Journal of Infectious Diseases
A patient with HIV infection developed the first episode of AIDS-defining opportunism (severe Candida albicans esophagitis) with an underlying CD4+ lymphocyte count of 1,025 cells/µL.
Roberto Manfredi, Sergio Sabbatani, Leonardo Calza   +2 more
doaj   +1 more source

Joint Dispersion Model with a Flexible Link [PDF]

arXiv, 2016
The objective is to model longitudinal and survival data jointly taking into account the dependence between the two responses in a real HIV/AIDS dataset using a shared parameter approach inside a Bayesian framework. We propose a linear mixed effects dispersion model to adjust the CD4 longitudinal biomarker data with a between-individual heterogeneity ...
arxiv  

Impact of aging : sporadic, and genetic risk factors on vulnerability to apoptosis in Alzheimer's disease [PDF]

, 2003
The identification of specific genetic (presenilin-1 [PS1] and amyloid precursor protein [APP] mutations) and environmental factors responsible for Alzheimer's disease (AD) has revealed evidence for a shared pathway of neuronal death.
Czech, Christian, Eckert, Anne, Frölich, Lutz, Kratzsch, Tilmann, Leutner, Silke, Maurer, Konrad, Müller, Walter E., Peters, Jürgen, Pradier, Laurent, Schindowski, Katharina, Steiner, Barbara, Touchet, Natalie   +11 more
core   +1 more source

Utility of Total Lymphocyte Count as an Affordable Surrogate for CD4 Lymphocyte Count in HIV Infected Nepali Patients

Journal of AIDS & Clinical Research, 2014
Introduction: AIDS is a disease of human immune system caused by Human Immunodeficiency Virus. Immunologically it is defined as the condition characterized by CD4 cell count less than 200 cells/mm3. In developing countries the resource are limited so that CD4 count is not easily available in every parts of the country and is too expensive to afford ...
Bishnu Prasad Uppadhya, Rama Gyawali, Sunil Poudel, Binod Kumar Yadav, Buddha Laxmi Prajapati, Suresh Prajapati, Swosti Acharya   +6 more
openaire   +2 more sources

Prevalence of Pulmonary tuberculosis and immunological profile of HIV co-infected patients in Northwest Ethiopia

BMC Research Notes, 2012
Background In sub-Saharan Africa, as high as 2/3 of tuberculosis patients are HIV/AIDS co-infected and tuberculosis is the most common cause of death among HIV/AIDS patients worldwide.
Wondimeneh Yitayih, Muluye Dagnachew, Belyhun Yeshambel   +2 more
doaj   +1 more source

Dynamical System Modeling Of Immune Reconstitution Following Allogeneic Stem Cell Transplantation Identifies Patients At Risk For Adverse Outcomes [PDF]

arXiv, 2014
Systems that evolve over time and follow mathematical laws as they do so, are called dynamical systems. Lymphocyte recovery and clinical outcomes in 41 allograft recipients conditioned using anti-thymocyte globulin (ATG) and 4.5 Gray total-body-irradiation were studied to determine if immune reconstitution could be described as a dynamical system ...
arxiv  

Fast Covariance Estimation for Sparse Functional Data [PDF]

arXiv, 2016
Smoothing of noisy sample covariances is an important component in functional data analysis. We propose a novel covariance smoothing method based on penalized splines and associated software. The proposed method is a bivariate spline smoother that is designed for covariance smoothing and can be used for sparse functional or longitudinal data.
arxiv