ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup +11 more
wiley +1 more source
Abstract figure legend The glia‐immune network involves the communication(s) of glia via immune signalling pathways. In neuro‐homeostasis these pathways have been shown to modulate key processes such as synaptic pruning and myelination. The dynamics of these processes is critical to CNS function.
Verity F. T. Mitchener +2 more
wiley +1 more source
Complement-Mediated Virus Infectivity Neutralisation by HLA Antibodies Is Associated with Sterilising Immunity to SIV Challenge in the Macaque Model for HIV/AIDS. [PDF]
Sterilising immunity is a desired outcome for vaccination against human immunodeficiency virus (HIV) and has been observed in the macaque model using inactivated simian immunodeficiency virus (SIV).
A Morner +61 more
core +2 more sources
Integration of maternal genome into the neonate genome through breast milk mRNA transcripts and reverse transcriptase [PDF]
Human milk samples contain microvesicles similar to the retroviruses. These microvesicles contain mRNA transcripts and possess reverse transcriptase activity. They contain about 14,000 transcripts representing the milk transcriptome.
Emin Oztas, M Irmak, Yesim Oztas
core +1 more source
Complement C2 receptor inhibitor trispanning: from man to schistosome [PDF]
Horizontal gene transfer (HGT), in relation to genetic transfer between hosts and parasites, is a little described mechanism. Since the complement inhibitor CRIT was first discovered in the human Schistosoma parasite (the causative agent of Bilharzia ...
Inal, Jameel
core +1 more source
Complement system activation contributes to the ependymal damage induced by microbial neuraminidase [PDF]
Background In the rat brain, a single intracerebroventricular injection of neuraminidase from Clostridium perfringens induces ependymal detachment and death.
A Ascherio +84 more
core +2 more sources
PreImplantation Factor (PIF) promotes HLA-G, -E, -F, -C expression in JEG-3 choriocarcinoma cells and endogenous progesterone activity [PDF]
BACKGROUND: Pregnancy success requires mandatory maternal tolerance of the semi/allogeneic embryo involving embryo-derived signals. Expression levels of PreImplantation Factor (PIF), a novel peptide secreted by viable embryos, correlate with embryo ...
Barnea, ER +7 more
core +2 more sources
A Compendium of Urinary Biomarkers Indicative of Glomerular Podocytopathy [PDF]
It is well known that glomerular podocyte injury and loss are present in numerous nephropathies and that the pathophysiologic consecution of disease hinges upon the fate of the podocyte.
Pichler Sekulic, Simona +1 more
core +2 more sources
Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to Lead Future Studies for Borrelia miyamotoi [PDF]
The emerging pathogen, Borrelia miyamotoi, is a relapsing fever spirochete vectored by the same species of Ixodes ticks that carry the causative agents of Lyme disease in the US, Europe, and Asia. Symptoms caused by infection with B.
Brandee L. Stone, Catherine A. Brissette
core +1 more source
LABRAD : Vol 41, Issue 2 - July 2015 [PDF]
An Overview of Immunoglobulin G4-Related Disease Plasma Neutrophil Gelatinase Associated Lipocalin (NGAL) a Marker of Acute Kidney Injury Celiac Disease: Biomarkers for Diagnosis and Monitoring Pathophysiology of Paroxysmal Nocturnal Haemoglobinuria and ...
Aga Khan Universiity Hospital, Karachi
core +1 more source

