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HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

The complement inhibitor CD59 and the lymphocyte function-associated antigen-3 (LFA-3, CD58) genes possess functional binding sites for the p53 tumor suppressor protein.

Anticancer research, 2002
p53 is an oncosuppressor protein, which acts via transcriptional and non-transcriptional mechanisms. The transcriptional function of p53 is mediated by specific responsive elements. In the present study we found active responsive elements, specific for the p53 within the 5'flanking region and within the first intron of the gene encoding for the CD59 ...
Gazouli, M., Kokotas, S., Zoumpourlis, Vassilis, Zacharatos, P., Mariatos, G., Kletsas, D., Perunovic, B., Athanasiou, Kyriakos, Kittas, C., Gorgoulis, V.   +9 more
openaire   +2 more sources

Plasma proteomics reveal SERPINA1 and CD59 as candidate biomarkers for COVID-19 severity stratification and prognosis prediction. [PDF]

Ann Med
Zhou Z, Liu Q, Ma S, Shi A, Tao Y, Hu T, Yan S, Chen Y, Ji X, Sun L, Zhang H, Song W, Zhang Z, Yang P, Zhai Z.   +14 more
europepmc   +1 more source

Advances in cryo-EM that have shaped mechanistic models of membrane-attack-complex assembly and regulation. [PDF]

IUCrJ
Noone DP, Bubeck D.
europepmc   +1 more source

The role of the complement system in gastrointestinal-related diseases. [PDF]

Front Immunol
Yong B, Luo Z, Luo B, Liu J, Zeng Z, Zheng X.   +5 more
europepmc   +1 more source

CD59 silencing enhances doxorubicin sensitivity in DLBCL cells and is associated with poor prognosis in patients treated with CHOP regimen. [PDF]

Clin Exp Med
Linzhu, Xianmusiya M, Wen S, Wu M, Li S, Liang X.   +5 more
europepmc   +1 more source

Complement system in cancer: friend or foe of immunotherapy. [PDF]

J Immunother Cancer
Shah HK, Prem S, Wu X, Liszewski MK, Atkinson JP, Singh AK, Kapoor V.   +6 more
europepmc   +1 more source

Role of NK cells in immune escape in patients with classical paroxysmal nocturnal haemoglobinuria. [PDF]

Clin Transl Med
Wang C, Yang Y, Wang W, Li L, Che M, Chen Y, Wang H, Liu Z, Li L, Liu H, Fu R.   +10 more
europepmc   +1 more source

Complement activation in kidney transplantation. [PDF]

Nephrol Dial Transplant
Kanbay M, Ozbek L, Guldan M, Akcin Z, Susal CC, Yilmaz AM, Akgul SU, Susal C.   +7 more
europepmc   +1 more source

Mesenchymal stem cell exosomes alleviate osteoarthritis by inhibiting complement activation via a CD59-dependent pathway. [PDF]

Arthritis Res Ther
Jiang Y, Ng CY, Seow DSK, Loh JT, Wong RCW, Hui JHP, Toh WS.   +6 more
europepmc   +1 more source