Results 61 to 70 of about 6,819 (179)
Provirus activation plus CD59 blockage triggers antibody-dependent complement-mediated lysis of latently HIV-1-infected cells [PDF]
, 2014 Latently HIV-1-infected cells are recognized as the last barrier toward viral eradication and cure. To purge these cells, we combined a provirus stimulant with a blocker of human CD59, a key member of the regulators of complement activation, to trigger ...
Amet, Tohti +10 more
core +2 more sources
Current Status of Kidney Xenotransplantation in Basic Research
Organ Medicine, Volume 3, Issue 2, Page 87-101, June 2026.Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley +1 more source
The diagnosis and management of the haematologic manifestations of lupus [PDF]
, 2016 Haematological manifestations in systemic lupus erythematosus (SLE) are frequently observed. They are diverse and range from mild to severe.
Castro, SG +2 more
core +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen +7 more
wiley +1 more source
Anaerobe‐Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition
American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.ABSTRACT Background Genital microbiome dysbiosis is an important risk factor for the sexual acquisition of human immunodeficiency virus (HIV) in both the male and female genital tracts. The vaginal, penile and urethral mucosae are distinct microenvironments with characteristic microbiome compositions.
Shirley Constable +6 more
wiley +1 more source
Reorganization of mouse sperm lipid rafts by capacitation [PDF]
, 2006 One of the hallmarks of mammalian sperm capacitation is the loss of cholesterol from the plasma membrane. Cholesterol has been associated with the formation of detergent insoluble membrane microdomains in many cell types, and sperm from several mammalian
Ramalie, Jenniffer R. +2 more
core +1 more source
Xenotransplantation, Volume 33, Issue 3, May/June 2026.ABSTRACT Objectives This study aimed to investigate the functional recovery of an 8‐gene‐edited pig heart after orthotopic xenotransplantation, the characteristics of the recipient's immune responses, and the efficacy of postoperative complication management to provide comprehensive experimental evidence for the clinical translation of xenogeneic ...
Xianzhi Wang +17 more
wiley +1 more source
Comparison of the proteome of adult and cord erythroid cells, and changes in the proteome following reticulocyte maturation [PDF]
, 2016 Cord blood stem cells are an attractive starting source for the production of red blood cells in vitro for therapy because of additional expansion potential compared to adult peripheral blood progenitors, and cord blood banks usually being more ...
Frayne, Jan +4 more
core +2 more sources
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao +3 more
wiley +1 more source
Limb regeneration in amphibians: immunological considerations [PDF]
, 2006 We review key aspects of what is known about limb regeneration in urodele and anuran amphibians, with a focus on the early events of the process that lead to formation of the regeneration blastema.
Mescher, Anthony L., Neff, Anton W.
core +2 more sources