Results 161 to 170 of about 38,724 (265)

The CD73-adenosine axis in melanoma: from multidimensional regulation to precision immunotherapy. [PDF]

Front Immunol
Liu X, Sun P, Chen C, Chen X.
europepmc   +1 more source

Indoxyl sulfate exacerbates chronic inflammation and susceptibility to severe infection via modulating T-cell CD73/adenosine signaling in chronic kidney disease. [PDF]

Ren Fail
Cao J, Nie Y, Cao X, Chen X, Bo J, Wang Y, Zou J, Ding X, Shen B, Xiang F.   +9 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Dual-targeting CD73/PD-L1 bifunctional inhibitor: a promising cancer immunotherapy strategy. [PDF]

Front Immunol
Du JJ, Wu S, Cheng S, Zeng X, Cheng B.
europepmc   +1 more source

Nrf2–Keap1 Axis Modulation by Phytofabricated Metal Oxide Nanoparticles in Mesenchymal Stem Cell Lineage Bias

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Phytofabricated metal oxide nanoparticles may activate the Nrf2–Keap1 axis through a dual‐stimulus mechanism, coupling nanoparticle‐derived ROS with phytochemical‐mediated Keap1 modification, steering mesenchymal stem cells toward osteogenic commitment — a mechanistic framework this review consolidates from current evidence.
Muhammad Irfan, Muhammad Taha, Syed Muhammad Faizan Asghar, Muhammad Raza   +3 more
wiley   +1 more source

IL-6 Upregulates CD73 in Human Placental Mesenchymal Stem Cells to Promote ATRA-Induced NB4 Cell Differentiation in Acute Promyelocytic Leukemia. [PDF]

Cancer Med
Qi R, Zhang H, Wu Y, Ma Y, Luan X.
europepmc   +1 more source

Applications of Mesenchymal Stromal Cells for Treatment of Diseases

MedComm, Volume 7, Issue 9, September 2026.
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley   +1 more source

Impaired regulation by purinergic signaling axis contributes to CD8+ T cell dysregulation in STAT3 gain of function. [PDF]

JCI Insight
Campos Duran JS, Knight MS, Sayed SU, Dalalo MC, Mauracher AA, Conrey P, Schultz AB, Hay CA, Lindell RB, Neale I, Yeakle K, Abrams ED, Schmitt EG, Thelin MA, Howard CA, Bluestein S, Seroogy CM, Pozos TC, Thatayatikom A, Lundgren IS, Gauthier A, Canna SW, Su HC, Keller MD, Delmonte OM, Forbes Satter LR, Holland SM, Bergerson JR, Leiding JW, Romberg N, Bailis W, Hunter CA, Freeman AF, Villarino AV, Anderson MS, Cooper MA, Vogel TP, Henrickson SE.   +37 more
europepmc   +1 more source

Cancer Neuroscience: From Local Neuro–Immune Microenvironments to Systemic Brain–Body Circuitry

MedComm, Volume 7, Issue 9, September 2026.
This review outlines the cancer neuroscience paradigm, spanning systemic brain–body circuitry and local neuro–immune–tumor microenvironments. We discuss how tumors promote axonogenesis and pseudo‐synapse formation, and how sensory neuropeptides, such as CGRP, contribute to CD8+ T‐cell exhaustion.
Mingxuan Xie, Yu Zhao, Xinruo Xing, Yuqiang Liu, Jungang Zhao, Maojin Yao, Jun Tang, Jianzhu Zhao   +7 more
wiley   +1 more source

Impact of CD73/CD155 Expression on Survival in Resected Epithelial Pleural Mesothelioma: A Retrospective Single-center Study. [PDF]

In Vivo
Nabe Y, Fujita Y, Hashimoto T, Tanaka K, Manabe T, Yoshimatsu K, Nemoto Y, Nishizawa N, Oyama R, Honda Y, Mori M, Matsumiya H, Kanayama M, Taira A, Takenaka M, Kuroda K, Shimajiri S, Tanaka F.   +17 more
europepmc   +1 more source