Results 141 to 150 of about 39,639 (239)

CD73 as a potential opportunity for cancer immunotherapy

, 2019
Introduction: Cancer cells apply various mechanisms to induce and enhance immune escape. The complex network of immune-response modulating factors in the tumor microenvironment is a reason for the difficulties encountered when attempting to treat many ...
Jadidi-Niaragh, Farhad, Kazemi, M.H., Yousefi, Mehdi, Raoofi Mohseni, Sahar, Azizi, Gholamreza, Ghalamfarsa, Ghasem, Hojjat-Farsangi, M., Jadidi-Niaragh, F., Kazemi, Mohammad Hossein, Masjedi, A., Yousefi, M., Masjedi, Ali, Raoofi Mohseni, S., Azizi, G., Ghalamfarsa, G., Hojjat-Farsangi, Mohammad   +15 more
core  

Radiolabeled Human Monoclonal Antibody 067-213 has the Potential for Noninvasive Quantification of CD73 Expression.

CD73 is an ectonucleotidase regulating extracellular adenosine concentration and plays an important role in adenosine-mediated immunosuppressive pathways.
925913, 925912, Saga, Tsuneo, Kurosawa, Yoshikazu, Higashi, Tatsuya, Aya, Sugyo, Sugyo, Aya, 925925, 925922, 925921, 925924, Tsuda, Hiroyuki, 925923, 925920, Kurosawa, Gene, Sudo, Hitomi, Atsushi, Tsuji, B Tsuji, Atsushi, Alexander, David, Tatsuya, Higashi, Tsuneo, Saga, 925919, 925918, 925915, Hitomi, Sudo, 925914, 925917, 925916   +27 more
core  

CD73: A Promising Biomarker in Cancer Patients [PDF]

Frontiers in Pharmacology, 2020
Turiello R., Pinto A., Morello S.
openaire   +3 more sources

CD73 targeted combination therapy reverses PD-1 inhibitor resistance in CD73-high PD-L1-negative NSCLC: Evidence from pleural effusion organoids. [PDF]

Glob Med Genet
Ren ZR, Wu L, Huang QL, Cai DX, Peng YL, Tang LB, Li JT, Zhu HY, Xu CR, Lu C, Chen ZH, Deng Y, Lin YJ, Zhou Q.   +13 more
europepmc   +1 more source

CD73-Overexpressing ADSCs Promote Neurogenic Bladder Repair via A2A-JAK1/STAT3-Mediated Modulation of Inflammation and Macrophage Polarization. [PDF]

Stem Cells Int
Zhu G, Jiang G, Huang J, He Y, Zhang Z, Zhang R, Yin X, Zhao K, Yang X, Bae WJ, Wang K.   +10 more
europepmc   +1 more source

The CD39-CD73-adenosine axis: a pivotal regulator of retinal homeostasis and diseases. [PDF]

Front Cell Dev Biol
Chen X, Ji J, Yao J, Chen P, Zhang J, Liu L, Wen X.   +6 more
europepmc   +1 more source

Pharmacological melatonin induces mitochondrial dysfunction and alters extracellular nucleotide metabolism and CD39/CD73 expression in human melanoma cells. [PDF]

Purinergic Signal
Ozelame BC, Mânica D, da Silva GB, Cardoso AM, Bagatini MD, Mânica A.   +5 more
europepmc   +1 more source

Enhanced CD33 CAR-NK cells secreting anti-CD73scFv overcome adenosine-mediated immunosuppression and improve anti-AML efficacy. [PDF]

J Immunother Cancer
Wang L, Gong S, Wang J, Bao Y, Mei N, Lu X, Chen W, Xi L, Zhang H, Chen X, Ning P, Fan X, Wang H.   +12 more
europepmc   +1 more source

Pantoprazole as a potential repurposed drug targeting the adenosinergic system in esophageal cancer. [PDF]

Med Chem Res
Simioni A, Weimer RD, de Souza JB, Citrini IV, da Rosa JA, Cardoso K, Delawi ME, Timmers LF, Morrone FB.   +8 more
europepmc   +1 more source

CD73 inhibition overcomes adaptive immune resistance to PARP inhibition in models of prostate cancer. [PDF]

J Clin Invest
Xie P, Ma R, Zhang M, Fan J, Tang H, Song L, Wan Y, Kuzel TM, Fang D, Cui W, Wu JD, Abdulkadir SA, Zhang Y, Patnaik A, Zhang B.   +14 more
europepmc   +1 more source