Results 151 to 160 of about 36,481 (278)
Journal of Periodontal Research, EarlyView.A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Recipient CD73 limits GVHD development.
, 2013 (A) Lethally irradiated WT (n = 10) or CD73 KO (n = 10) BALB/c mice were given i.v. injections of 5×106 T cell depleted BM cells from B6 mice donors alone (n = 5) or with 2×107 splenocytes from WT B6 donors. Lethally irradiated WT (n = 10) or CD73 KO (n =
Yi Zhang (9093) +5 more
core +1 more source
Periodontology 2000, EarlyView.Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi +4 more
wiley +1 more source
Therapeutic Value of CD73 as a Biomarker in Human Cancer
, 2019 Context: Over the past several years, biomarkers have emerged as a diagnostic and therapeutic tool for cancer therapy. CD73 (ecto-5'-nucleotidase) which is a cell surface ectonucleotidase, mediates the conversion of extracellular Adenosine monophosphate (
Hashemi, Mehrdad +3 more
core +1 more source
Understanding exosomes in regenerative dentistry
Periodontology 2000, EarlyView.Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
, 2013 Recent studies have shown that Abs that target the cell-surface enzyme CD73 (ecto-5'-nucleotidase) reduce growth of primary tumors and metastasis in syngenic mice by inhibiting the catalytic activity of CD73, and thus increasing the activity of cytotoxic
Ditzel, Henrik J +6 more
core +1 more source
Methods and tools for studying ecto-5'-nucleotidase (CD73)
Ecto-5’-nucleotidase (CD73), a glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed mainly in the membranes of immune and endothelial cells and released in exosomes or as a soluble protein, has emerged as a potential target in cancer ...
Idris, Riham Mohammed Omer Ali
core +1 more source
Proposed mechanisms of isoflurane-mediated endothelial CD73 generation.
, 2014 We hypothesize that isoflurane via Rho kinase activation releases endothelial microparticles containing CD73. Increased endothelial microparticle CD73 converts AMP to adenosine which produces cytoprotective effects on neighboring endothelial cells or ...
Kevin M. Brown (182605) +4 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida +4 more
wiley +1 more source