Results 131 to 140 of about 38,724 (265)

The role of the adenosinergic pathway in resistance to hypomethylating agents in patients with high‐risk myelodysplastic syndromes

British Journal of Haematology, EarlyView.
George Vrachiolias, Eleftheria Lamprianidou, Athanasios Tasis, Theodoros Spyropoulos, Despoina Dimitriou, Chryssa Kymparidou, Christina Misidou, Konstantinos Liapis, Emmanouil Spanoudakis, Maria Koffa, Menelaos Papoutselis, Iliana Stamatiou, Elsa Bernard, Elli Papaemmanuil, Ioannis Mitroulis, Ioannis Kotsianidis   +15 more
wiley   +1 more source

Inhibition by adenosine of fEPSP recordings in hippocampal slices from CD73^+/+ and CD73^−/− mice.

, 2013
(a) Representative traces of fEPSPs; numbers 1–6 correspond to before and during superfusion of slices with adenosine (10, 25, 50 or 100 µM) or adenosine (100 µM) and DPCPX (1 µM) as indicated in (b).
Wei Xiong (58411), Chao Sun (139686), Benedict C. Albensi (318170), Fiona E. Parkinson (318171), Stephanie Chu (318169), Dali Zhang (318168)   +5 more
core   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

A novel role of CD73-IFNγ signalling axis in human mesenchymal stromal cell mediated inflammatory macrophage suppression

Regenerative Therapy
Introduction: Immunomodulation is the predominant mechanism via which Mesenchymal stromal cells (MSCs) mediate their therapeutic benefits. However, inconsistent success in numerous clinical trials warrants a better understating of the molecular ...
Shashank Chandanala, Govind Mohan, David-Luther Manukonda, Anujith Kumar, Jyothi Prasanna   +4 more
doaj   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

MedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

T Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Bone Loss via CD39 and CD73-Mediated ATP Hydrolysis

International Journal of Nanomedicine
Xiaoshan Yang,1– 3,* Yang Zhou,2,3,* Fuxing Zhou,4,* Lili Bao,2,3 Zhengyan Wang,5 Zihan Li,2,3 Feng Ding,2,3 Huijuan Kuang,6,7 Huan Liu,8 Shenglong Tan,1 Xinyuan Qiu,1 Huan Jing,9 Shiyu Liu,2,3 Dandan Ma1 1Department of Endodontics ...
Yang X, Zhou Y, Zhou F, Bao L, Wang Z, Li Z, Ding F, Kuang H, Liu H, Tan S, Qiu X, Jing H, Liu S, Ma D   +13 more
doaj  

CD73 [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Methods and tools for studying ecto-5'-nucleotidase (CD73)

Ecto-5’-nucleotidase (CD73), a glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed mainly in the membranes of immune and endothelial cells and released in exosomes or as a soluble protein, has emerged as a potential target in cancer ...
Idris, Riham Mohammed Omer Ali
core   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

The Journal of Pathology, Volume 270, Issue 2, Page 139-162, October 2026.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi, Irene Torresan, Emilio Francesco Giunta, Sara Bleve, Nicole Brighi, Elisa Tassinari, Sofia Zanuccoli, Maria Concetta Cursano, Cristian Lolli   +8 more
wiley   +1 more source