Results 131 to 140 of about 39,639 (239)
Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min +2 more
wiley +1 more source
Background: CD73 is adenosine generation molecule, which is involved in the immune regulation. However, the roles of CD73 in the tumor microenvironment remain unknown.
Chen Chen, Sasa Liu, Yanfen Ma
doaj +1 more source
ABSTRACT Aim Dental pulp‐derived cells have attracted attention as an accessible source of mesenchymal stem cell‐like cells for bone regeneration. However, donor‐to‐donor variability in osteogenic potential remains a challenge for their clinical application.
Makoto Watanabe +11 more
wiley +1 more source
ABSTRACT Hepatocellular carcinoma (HCC), a lethal form of liver cancer, continues to show rising mortality rates despite advancements in immunotherapies. This highlights the need for more effective treatments. Recent studies linked the presence of B cells within human tumors, including HCC, to improved responses to immunotherapy and better prognoses ...
Fang Wang +3 more
wiley +1 more source
Senescent Mesenchymal Stromal Cells Drive Stem Cell Aging Through Dysregulated Chemokine Synthesis
Senescent MSCs do more than fuel inflammaging: they disrupt the chemokine signals that maintain stem cell function. We propose that restoring this signaling balance through senolytics, senomorphics, or MSC rejuvenation may preserve regenerative capacity during aging. ABSTRACT Aging is accompanied by a progressive decline in tissue regenerative capacity,
Shaianne N. Stein, Lorena R. Braid
wiley +1 more source
Lung sections were stained with antibodies against CD73. (A) Lung section from a Stage 0 COPD patient. (B) Lung section from a Mild IPF patient. (C) Lung section from a Stage 4 COPD patient. (D) Lung section from a Severe IPF patient.
Yang Zhou (65942) +4 more
core +1 more source
CD73 expression on T helper cells in vitro and in vivo.
A: CD73 expression on indicated live CD4+ T helper cell subsets after three days of ulture in vitro, numbers indicate mean % +/- S.D. from three separate experiments.
Gerard Hernandez-Mir (3833335) +1 more
core +1 more source
The 5'-Ectoenzyme Cd73 Promotes Toxoplasma Gondii Persistence In The Cns While Limiting Systemic Immunopathology [PDF]
The protozoan pathogen Toxoplasma gondii is a highly successful parasite that infects up to a third of the world's population, causing morbidity and mortality in the immunocompromised and when acquired congenitally. As an obligate intracellular pathogen,
Mahamed, Deeqa
core
Xiaoshan Yang,1– 3,* Yang Zhou,2,3,* Fuxing Zhou,4,* Lili Bao,2,3 Zhengyan Wang,5 Zihan Li,2,3 Feng Ding,2,3 Huijuan Kuang,6,7 Huan Liu,8 Shenglong Tan,1 Xinyuan Qiu,1 Huan Jing,9 Shiyu Liu,2,3 Dandan Ma1 1Department of Endodontics ...
Yang X +13 more
doaj

