Results 121 to 130 of about 36,605 (250)
Advances in Immunological Combination Therapy for Colorectal Cancer
iMetaMed, EarlyView.Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu +7 more
wiley +1 more source
Inhibition by ATP of fEPSP recordings in hippocampal slices from CD73+/+ and CD73−/− mice. [PDF]
, 2013 (a) Representative traces of fEPSPs; numbers 1–6 correspond to before and during superfusion of slices with ATP (10, 25, 50 or 100 µM) or ATP (100 µM) and DPCPX (1 µM) as indicated in (b).
Wei Xiong (58411) +5 more
core +1 more source
Journal of Hematology & Oncology, 2019 Background Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide because of rapid progression and high incidence of metastasis or recurrence.
Xiao-Lu Ma +16 more
doaj +1 more source
The regulation of stem cell fate and its application in neural regeneration
Interdisciplinary Medicine, EarlyView.Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Journal of Breast CancerCD39 (ENTPD1, ectonucleoside triphosphate diphosphohydrolase-1) and CD73 (NT5E, 5'-nucleotidase) are mediators of adenosine release in the tumor microenvironment (TME), and adenosine has the effect of overcoming anti-tumor immunity. This CD39-CD73-adenosine pathway is thought that play a role in immune suppression and promotion of tumor growth and ...
Eunhye Kang +4 more
openaire +2 more sources
Expression of CD39 and CD73 Ectonucleotidases in Interferon--Treated Human Wharton\'s Jelly Mesenchymal Stem Cells [PDF]
Research in Molecular MedicineBackground: Mesenchymal stem cells (MSCs) exhibit substantial immunomodulatory properties. Interferon gamma (IFN-γ) exposure has been shown to enhance the immunoregulatory capacity of MSCs.
Leila Pirdel, Manijeh Pirdel
doaj
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo +5 more
wiley +1 more source
Recipient CD73 limits GVHD development. [PDF]
, 2013 (A) Lethally irradiated WT (n = 10) or CD73 KO (n = 10) BALB/c mice were given i.v. injections of 5×106 T cell depleted BM cells from B6 mice donors alone (n = 5) or with 2×107 splenocytes from WT B6 donors. Lethally irradiated WT (n = 10) or CD73 KO (n =
Yi Zhang (9093) +5 more
core +1 more source
PLoS ONE, 2014 Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation.
Mihwa Kim +4 more
doaj +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley +1 more source