Results 1 to 10 of about 25,955 (200)

Pan-cancer single-cell transcriptomic analysis reveals CD83 as a hallmark of tumor-associated neutrophils with senescent and pro-tumor properties [PDF]

Computational and Structural Biotechnology Journal
Neutrophils, the most prevalent and efficient immune responders to pathogens, play vital roles in tumor progression and metastasis. Sustained neutrophil infiltration into tumor has been consistently linked to unfavorable clinical outcomes. Despite recent
Yimin Wang, Yuan Meng, Kanchao Chen, Aihua Li, Jinqiang Yan, Jie Ding, Bingwu Yang, Linlin Tang, Bin Ding, Siyuan Chen, Song Chen, Fengyu Chen, Tong Chen, Yan Zhang, Qin Zheng, Chao Chen, Sizhou Feng   +16 more
doaj   +2 more sources

Analysis of CD83 antigen expression in human breast fibroadenoma and adjacent tissue [PDF]

São Paulo Medical Journal, 2011
CONTEXT AND OBJECTIVE: Dendritic cell maturation is considered essential for starting an immune response. The CD83 antigen is an important marker of dendritic cell maturation.
Marcus Nascimento Borges, Gil Facina, Ismael Dale Cotrin Guerreiro Silva, Angela Flávia Logullo Waitzberg, Afonso Celso Pinto Nazario   +4 more
doaj   +2 more sources

Molecular cloning and characterization of duck CD83 and its effect on H9N2 avian influenza virus replication [PDF]

Poultry Science
Cluster of Differentiation 83 (CD83) is a multifunctional regulatory molecule that has been identified in several mammals, birds, and fishes; however, no reports have described CD83 in ducks to date.
Huinan Li, Xiaojing Xin, Zhe Yin, Chao Dong, Feng Li, Yujing Liu, Xinru Kong, Liyue Wang, Juan Wang, Fei Yu, Shanshan Huo   +10 more
doaj   +2 more sources

Reduced tolerogenic factor sCD83 in NMOSD and relapsing MOGAD: a potential new therapeutic pathway [PDF]

Frontiers in Immunology
BackgroundNeuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are autoimmune central nervous system disorders with poorly understood immune pathways. CD83 plays a crucial role in the
Ariel Rechtman, Ariel Rechtman, Omri Zveik, Omri Zveik, Lyne Shweiki, Lyne Shweiki, Garrick Hoichman, Garrick Hoichman, Garrick Hoichman, Tal Friedman-Korn, Tal Friedman-Korn, Livnat Brill, Livnat Brill, Adi Vaknin-Dembinsky, Adi Vaknin-Dembinsky   +14 more
doaj   +2 more sources

Transdifferentiation of neutrophils facilitates the establishment of infection by Leishmania donovani parasites [PDF]

Infection and Immunity
Neutrophil transdifferentiation involves the acquisition of dendritic cell-like properties, challenging the traditional view of neutrophils being solely phagocytes. The presence of transdifferentiated neutrophils is established in Visceral Leishmaniasis,
Madhurima Roy, Aniruddha Bagchi, Chaitali Karmakar, Mitali Chatterjee   +3 more
doaj   +2 more sources

IRX-2, a Novel Immunotherapeutic, Enhances Functions of Human Dendritic Cells [PDF]

, 2013
Background: In a recent phase II clinical trial for HNSCC patients, IRX-2, a cell-derived biologic, promoted T-cell infiltration into the tumor and prolonged overall survival. Mechanisms responsible for these IRX-2-mediated effects are unknown.
A Lopez-Albaitero, A Pinzon-Charry, AD Rapidis, B Almand, B Schilling, Bastian Schilling, C Reis e Sousa, C Sadhu, C Visus, D Agnello, Derya Unutmaz, DI Gabrilovich, DS Heo, DY Ma, E Procko, GG Kim, GT Wolf, H Jonuleit, H Jonuleit, H Okada, IK Poon, J Banchereau, James Egan, JE Egan, JM Kirkwood, L Frasca, LH Butterfield, M Ahmadi, M Temponi, Malgorzata Harasymczuk, MC Dieu, MR Young, N Bandoh, NL Berinstein, P Chaux, P Kalinski, P Langlade-Demoyen, Patrick Schuler, R Muthuswamy, S Amigorena, Soldano Ferrone, T Ogino, Theresa L. Whiteside, TK Hoffmann, TK Hoffmann, TL Whiteside, TL Whiteside, X Wang   +47 more
core   +31 more sources

Novel approaches to increase resistance to acute respiratory infections

RUDN Journal of Medicine, 2021
Relevance . Respiratory infections are the most common in the world. In order to prevent epidemics, there is a need to improve the strategies for organizing medical care and develop new approaches in order to increase the nonspecific resistance, mobilize
Svetlana V. Guryanova, Natalia A. Kudryashova, Anastasiya A. Kataeva, Bubusaira T. Orozbekova, Natalia V. Kolesnikova, Alexandr G. Chuchalin   +5 more
doaj   +1 more source

Intestinal Epithelial Cell-Derived CD83 Contributes to Regulatory T-Cell Generation and Inhibition of Food Allergy

Journal of Innate Immunity, 2021
The mechanism of generation of antigen-specific regulatory T cells (Treg) is not fully understood yet. This study aimed to investigate the role of intestinal epithelial cell (IEC)-derived CD83 in the Treg generation in the intestine.
Yong Yu, Qiao-Ruo Jin, Yang Mi, Jiang-Qi Liu, Zhi-Qiang Liu, Shuai Wang, Zhi-Gang Liu, Ping-Chang Yang, Peng-Yuan Zheng   +8 more
doaj   +1 more source

Microglial expression of CD83 governs cellular activation and restrains neuroinflammation in experimental autoimmune encephalomyelitis

Nature Communications, 2023
Microglial activation during neuroinflammation is crucial for coordinating the immune response against neuronal tissue, and the initial response of microglia determines the severity of neuro-inflammatory diseases.
Pia Sinner, Katrin Peckert-Maier, Hashem Mohammadian, Christine Kuhnt, Christina Draßner, Vasiliki Panagiotakopoulou, Simon Rauber, Mathias Linnerbauer, Zhana Haimon, Dmytro Royzman, Deborah Kronenberg-Versteeg, Andreas Ramming, Alexander Steinkasserer, Andreas B. Wild   +13 more
doaj   +1 more source

CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation

Frontiers in Immunology, 2023
Excessive macrophage (Mφ) activation results in chronic inflammatory responses or autoimmune diseases. Therefore, identification of novel immune checkpoints on Mφ, which contribute to resolution of inflammation, is crucial for the development of new ...
Katrin Peckert-Maier, Pia Langguth, Astrid Strack, Lena Stich, Petra Mühl-Zürbes, Christine Kuhnt, Christina Drassner, Elisabeth Zinser, Marius Wrage, Jochen Mattner, Alexander Steinkasserer, Dmytro Royzman, Andreas B. Wild   +12 more
doaj   +1 more source