Results 21 to 30 of about 25,955 (200)
The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population [PDF]
The Journal of Immunology, 2016 Abstract CD83 is a member of the Ig gene superfamily, first identified in activated lymphocytes. Since then, CD83 has become an important marker for defining activated human dendritic cells (DC). Several potential CD83 mRNA isoforms have been described, including a soluble form detected in human serum, which may have an immunosuppressive
Xinsheng Ju +20 more
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Application of CD83 and HSF5 to Identify Antemortem and Postmortem Skin Burns
Fayixue Zazhi, 2021 ObjectiveTo explore the forensic application value of cluster of differentiation 83 （CD83） and heat shock transcription factor 5（HSF5） in identifying antemortem and postmortem skin burns.MethodsThrough reverse transcription real-time quantitative ...
ZHAO Long-rui +5 more
doaj +1 more source
Human Decidua Contains Potent Immunostimulatory CD83+ Dendritic Cells [PDF]
The American Journal of Pathology, 2000 Dendritic cells (DCs) are sentinel cells of the immune system important in initiating antigen-specific T-cell responses to microbial and transplantation antigens. DCs are particularly found in surface tissues such as skin and mucosa, where the organism is threatened by infectious agents.
U, Kämmerer +6 more
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Homologs of CD83 from Elasmobranch and Teleost Fish [PDF]
The Journal of Immunology, 2004 Abstract Dendritic cells are one of the most important cell types connecting innate and adaptive immunity, but very little is known about their evolutionary origins. To begin to study dendritic cells from lower vertebrates, we isolated and characterized CD83 from the nurse shark (Ginglymostoma cirratum (Gici)) and rainbow trout ...
Yuko, Ohta +7 more
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CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma
Haematologica, 2018 Chemotherapy and hematopoietic stem cell transplantation are effective treatments for most Hodgkin lymphoma patients, however there remains a need for better tumor-specific target therapy in Hodgkin lymphoma patients with refractory or relapsed disease ...
Ziduo Li +21 more
doaj +1 more source
Oscillation dynamics underlie functional switching of NF-κB for B-cell activation. [PDF]
, 2016 Transcription factor nuclear factor kappa B (NF-κB) shows cooperative switch-like activation followed by prolonged oscillatory nuclear translocation in response to extracellular stimuli.
Aihara, Kazuyuki +7 more
core +1 more source
Anisakis pegreffii impacts differentiation and function of human dendritic cells [PDF]
, 2018 Human dendritic cells (DCs) show remarkably phenotypic changes when matured in presence of helminth-derived products. These modifications frequently elicited a polarization towards Th2 cells and regulatory T cells thus contributing to immunological ...
Allen +55 more
core +1 more source
CD83 expression regulates antibody production in response to influenza A virus infection
Virology Journal, 2020 Background CD83 is known to regulate lymphocyte maturation, activation, homeostasis, and antibody response to immunization and infection. While CD83 has a major part in B cell function, its role in influenza A virus infection has not yet been ...
Madhav Akauliya +5 more
doaj +1 more source
Inhibition of Cd83 Cell Surface Expression during Dendritic Cell Maturation by Interference with Nuclear Export of Cd83 mRNA [PDF]
The Journal of Experimental Medicine, 2000 Dendritic cells (DCs), nature's adjuvant, must mature to sensitize T cells. However, although the maturation process is essential, it is not yet fully understood at the molecular level. In this study, we investigated the course of expression of the unique hypusine-containing protein eukaryotic initiation factor 5A (eIF-5A), which is part of a ...
M, Kruse +7 more
openaire +2 more sources
npj Vaccines, 2021 The immunogenicity and protective efficacy of vaccines can be enhanced by the selective delivery of antigens to the antigen-presenting cells (APCs).
Angita Shrestha +6 more
doaj +1 more source