Results 31 to 40 of about 14,542 (144)
CD83 Antibody Inhibits Human B Cell Responses to Antigen as well as Dendritic Cell–Mediated CD4 T Cell Responses [PDF]
The Journal of Immunology, 2018 Abstract Anti-CD83 Ab capable of Ab-dependent cellular cytotoxicity can deplete activated CD83+ human dendritic cells, thereby inhibiting CD4 T cell–mediated acute graft-versus-host disease. As CD83 is also expressed on the surface of activated B lymphocytes, we hypothesized that anti-CD83 would also inhibit B cell responses to ...
Kuan Y Wong +5 more
openaire +3 more sources
Mediators of Inflammation, 2019 Behçet’s disease (BD) is an autoinflammatory disease that can lead to life- and sight-threating complications. Dendritic cells (DCs) are the most potent antigen-presenting cells that can regulate multiple inflammatory pathways.
S. M. Shamsul Islam +3 more
doaj +1 more source
Immunophenotyping of Sheep Paraffin-Embedded Peripheral Lymph Nodes
Frontiers in Immunology, 2018 Sheep are not only a major livestock species globally, they are also an important large animal model for biomedical research and have contributed to our understanding of the ontogeny and architecture of the mammalian immune system.
Eleonora Melzi +4 more
doaj +1 more source
CD83 modulates B cell function in vitro: increased IL-10 and reduced Ig secretion by CD83Tg B cells.
PLoS ONE, 2007 The murine transmembrane glycoprotein CD83 is an important regulator for both thymic T cell maturation and peripheral T cell responses. Recently, we reported that CD83 also has a function on B cells: Ubiquitous transgenic (Tg) expression of CD83 ...
Birte Kretschmer +7 more
doaj +1 more source
Acquired Protective Immunity in Atlantic Salmon Salmo salar against the Myxozoan Kudoa thyrsites Involves Induction of MHIIβ + CD83 + Antigen-Presenting Cells [PDF]
Infection and Immunity, 2018 ABSTRACT The histozoic myxozoan parasite Kudoa thyrsites causes postmortem myoliquefaction and is responsible for economic losses to salmon aquaculture in the Pacific Northwest. Despite its importance, little is known about the host-parasite relationship, including the host response to infection.
Braden, Laura M +8 more
openaire +4 more sources
Frontiers in Immunology, 2022 Here we show that soluble CD83 induces the resolution of inflammation in an antigen-induced arthritis (AIA) model. Joint swelling and the arthritis-related expression levels of IL-1β, IL-6, RANKL, MMP9, and OC-Stamp were strongly reduced, while Foxp3 was
Dmytro Royzman +17 more
doaj +1 more source
Pharmaceutics, 2022 Rheumatoid arthritis (RA) is a disabling autoimmune disease whose treatment is ineffective for one-third of patients. Thus, the immunomodulatory potential of mesenchymal stromal/stem cells (MSCs) makes MSC-based therapy a promising approach to RA.
Paula Laranjeira +12 more
doaj +1 more source
Folia Histochemica et Cytobiologica, 2009 Propionibacterium acnes (P. acnes) has been implicated in the pathogenesis of acne vulgaris which is the most common cutaneous disorder. It has a proinflammatory activity and takes part in immune reactions modulating the Th1/Th2 cellular response.
Maria Juszkiewicz-Borowiec +7 more
doaj +1 more source
Journal of Immunotoxicology, 2022 Micro- and nanoplastics (MNP) are ubiquitously present in the environment due to their high persistence and bioaccumulative properties. Humans get exposed to MNP via various routes and consequently, they will encounter dendritic cells (DC) which are ...
Annemijne E. T. van den Berg +7 more
doaj +1 more source
Frontiers in Immunology, 2022 ObjectiveTo explore the correlation between postpartum hepatitis and changes of plasmacytoid dendritic cells’ (pDC) function and frequency in hepatitis B e antigen (HBeAg)-positive pregnant women with chronic hepatitis B virus (HBV) infection ...
Fuchuan Wang +26 more
doaj +1 more source