Results 101 to 110 of about 3,939 (188)

Boyden Chamber Assay to Study of Cell Migration Induced by Metalloprotease Cleaved-CD95L

, 2017
International audienceCD95 receptor, also called Fas or Apo-1, is a member of the tumor necrosis factor receptors (TNF-R) superfamily (Itoh and Nagata, J Biol Chem 268:10932-10937, 1993).
Legembre, Patrick, Poissonnier, Amanda, Patrick Legembre, Amanda Poissonnier   +3 more
core   +1 more source

Die Rolle des CD95/CD95L-Systems bei der Aktivierung primärer humaner T-Lymphozyten [PDF]

, 2010
Der Todesfaktor CD95L ist bekannt für seine Fähigkeit apoptotischen Zelltod in CD95-sensitiven Zellen zu induzieren. Es häufen sich jedoch seit einiger Zeit Hinweise auf zusätzliche anti-apoptotische Funktionen des CD95/CD95L-Systems in verschiedenen ...
Paulsen, Maren
core   +1 more source

Liquid Chromatography–High Resolution Mass Spectrometry Method to Study Sphingolipid Metabolism Changes in Response to CD95L

, 2017
International audienceSphingolipids are sphingoid base-containing lipids, among which some metabolites behave as bioactive molecules in various biological processes, including cell death.
Bassam Badran, Bilal, Fatima, Justine Bertrand-Michel, Fatima Bilal, Badran, Bassam, Pérès, Michaël, Thierry Levade, Nathalie Andrieu-Abadie, Pauline Le Faouder, Le Faouder, Pauline, Ahmad Daher, Bruno Ségui, Andrieu-Abadie, Nathalie, Daher, Ahmad, Michaël Pérès, Bertrand-Michel, Justine, Levade, Thierry, Aude Dupuy, Dupuy, Aude, Ségui, Bruno   +19 more
core   +1 more source

Fas/FasL在宫颈癌组织中的表达及意义

Zhongguo shiyan zhenduanxue, 2011
肿瘤不仅是增殖和分化异常的疾病,同时也是凋亡异常的疾病,肿瘤常表现出细胞增生亢进及凋亡减少。Fas/FasL系统是凋亡相关基因[1,2]。Fas,又名CD95或APO-1,属于肿瘤坏死因子受体（TN-FR）和神经生长因子受体（NGFR）家族。人Fas基因定位于第10号染色体长臂2区（10q24.1）,包含8个内含子和9个外显子。Fas配体（Fasl）,又称CD95L,
张妍, 张文颖, 周玲, 王莉
doaj  

Evolutionary regulation of human Fas ligand (CD95L) by plasmin in solid cancer immunotherapy

Nature Communications
Despite sharing >98% genomic similarity, humans are more likely to develop cancers than our closest living ancestors, the nonhuman primates. Here, we unexpectedly discover that, unlike chimpanzee and other primates, a critical embryonic development ...
Brice E. N. Wamba, Tanmoy Mondal, Francis Freenor V, Mehr Shaheed, Oliver Pang, Daniel Bedinger, Patrick Legembre, Laurent Devel, Sanchita Bhatnagar, Gary Scott Leiserowitz, Jogender Tushir-Singh   +10 more
doaj   +1 more source

CD95/Fas ligand induced toxicity. [PDF]

Biochem Soc Trans, 2023
Haluck-Kangas A, Peter ME.
europepmc   +1 more source

A simple and broadly applicable nanobody-based approach to generate potent TNFR agonists. [PDF]

Cell Death Dis
Lang I, Zaitseva O, Glöckler A, Siegmund D, Sheta D, Mouhandes B, Weisenberger D, Schäfer V, Stepanzow S, Schneider T, Beilhack A, Crauel A, Kilisch M, Funk LM, Götzke H, Frey S, Wajant H.   +16 more
europepmc   +1 more source

CD95/Fas stoichiometry in future precision medicine. [PDF]

Cell Death Differ
Sica M, Roussel M, Legembre P.
europepmc   +1 more source

DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells? [PDF]

Oncotarget, 2023
Patel M, Peter ME.
europepmc   +1 more source

Semisynthetic Ferritin Nanocages for Flexible, Site-Specific Targeting and Ligand-Free Activation of Membrane Receptors. [PDF]

Nano Lett
Neusch A, Siepe C, Zitzke L, Fux AC, Monzel C.   +4 more
europepmc   +1 more source