Results 81 to 90 of about 9,042 (190)

Image_3_Platelets interact with CD169+ macrophages and cDC1 and enhance liposome-induced CD8+ T cell responses.jpeg

, 2023
Historically platelets are mostly known for their crucial contribution to hemostasis, but there is growing understanding of their role in inflammation and immunity.
Maarten K. Nijen Twilhaar (11197329), Ilse Jongerius (246324), Admar Verschoor (251200), Katarzyna Olesek (5722949), Cees van Kooten (795358), Alsya J. Affandi (11197326), Joanna Grabowska (5722952), Mieke C. Brouwer (12755072), Gert Storm (21109), Valentine Léopold (17415510), Cornelis van ‘t Veer (694059), Yvette van Kooyk (7462034), Joke M. M. den Haan (7500083)   +12 more
core   +1 more source

Profiling MHC II immunopeptidome of blood‐stage malaria reveals that cDC1 control the functionality of parasite‐specific CD4 T cells

EMBO Molecular Medicine, 2017
In malaria, CD4 Th1 and T follicular helper (TFH) cells are important for controlling parasite growth, but Th1 cells also contribute to immunopathology. Moreover, various regulatory CD4 T‐cell subsets are critical to hamper pathology.
Marion Draheim, Myriam F Wlodarczyk, Karine Crozat, Jean‐Michel Saliou, Tchilabalo Dilezitoko Alayi, Stanislas Tomavo, Ali Hassan, Anna Salvioni, Claudia Demarta‐Gatsi, John Sidney, Alessandro Sette, Marc Dalod, Antoine Berry, Olivier Silvie, Nicolas Blanchard   +14 more
doaj   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Linked collectors and determiners for: Colección de Macroinvertebrados Acuáticos de la Amazonia Colombiana.

Natural history specimen data linked to collectors and determiners held within, "Colección de Macroinvertebrados Acuáticos de la Amazonia Colombiana".
Bionomia
core   +1 more source

NK cells stimulate recruitment of cDC1 into the tumor microenvironment promoting cancer immune control

, 2020
Conventional type 1 dendritic cells (cDC1) are critical for antitumor immunity, and their abundance within tumors is associated with immune-mediated rejection and the success of immunotherapy.
Neil C Rogers (9071588), Jan P Böttcher (9071576), Stefano Sammicheli (337566), Caetano Reis e Sousa (599615), Santiago Zelenay (9071591), Eduardo Bonavita (9071579), Probir Chakravarty (755948), Erik Sahai (829065), Hanna Blees (9071582), Mar Cabeza Cabrerizo (9071585)   +9 more
core  

Functions of cDC1 in Mediating CD4+ Help for CD8+ T cells [PDF]

Classical dendritic cells (cDCs) are specialized antigen presenting cells that comprise distinct subsets distinguished by transcriptional developmental differences and in the types of immune responses they initiate. Classical type 1 dendritic cells (cDC1)
Wu, Renee
core   +1 more source

TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses

Nature Communications, 2021
Acquisition of dying tumor cell-associated antigens is an essential step for the initiation of anti-tumor immune response by conventional type 1 dendritic cells (cDC1).
Nicoletta Caronni, Giulia Maria Piperno, Francesca Simoncello, Oriana Romano, Simone Vodret, Yuichi Yanagihashi, Regine Dress, Charles-Antoine Dutertre, Mattia Bugatti, Pierre Bourdeley, Annalisa Del Prete, Tiziana Schioppa, Emilia Maria Cristina Mazza, Licio Collavin, Serena Zacchigna, Renato Ostuni, Pierre Guermonprez, William Vermi, Florent Ginhoux, Silvio Bicciato, Shigekatzu Nagata, Federica Benvenuti   +21 more
doaj   +1 more source

Porcine Reproductive and Respiratory Syndrome Virus Type 1.3 Lena Triggers Conventional Dendritic Cells 1 Activation and T Helper 1 Immune Response Without Infecting Dendritic Cells

Frontiers in Immunology, 2018
Porcine Reproductive and Respiratory Syndrome virus (PRRSV) is an arterivirus responsible for highly contagious infection and huge economic losses in pig industry. Two species, PRRSV-1 and PRRSV-2 are distinguished, PRRSV-1 being more prevalent in Europe.
Elise Bordet, Fany Blanc, Mathieu Tiret, Elisa Crisci, Elisa Crisci, Edwige Bouguyon, Patricia Renson, Patricia Renson, Patricia Renson, Pauline Maisonnasse, Mickael Bourge, Jean-Jacques Leplat, Elisabetta Giuffra, Luc Jouneau, Isabelle Schwartz-Cornil, Olivier Bourry, Olivier Bourry, Nicolas Bertho   +17 more
doaj   +1 more source

Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific CD8+ T cells in pancreatic cancer

JCI Insight, 2022
We investigate how myeloid subsets differentially shape immunity to pancreatic ductal adenocarcinoma (PDA). We show that tumor antigenicity sculpts myeloid cell composition and functionality.
Adam L. Burrack, Zoe C. Schmiechen, Michael T. Patterson, Ebony A. Miller, Ellen J. Spartz, Meagan R. Rollins, Jackson F. Raynor, Jason S. Mitchell, Tsuneyasu Kaisho, Brian T. Fife, Ingunn M. Stromnes   +10 more
doaj   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source