Results 51 to 60 of about 29,622 (230)

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Dynamic recruitment of Cdc2 to specific microtubule structures during mitosis [PDF]

, 2001
A-type cyclin-dependent kinases (CDKs), also known as cdc2, are central to the orderly progression of the cell cycle. We made a functional Green Fluorescent Protein (GFP) fusion with CDK-A (Cdc2-GFP) and followed its subcellular localization during the ...
Binarova, P., Heberle-Bors, E., Bogre, L., Doonan, J., David, J. P., Drykova, D., Weingartner, M., Schweighofer, A.   +7 more
core  

Microenvironmental and cell intrinsic factors governing human cDC2 differentiation and monocyte reprogramming

Frontiers in Immunology, 2023
cDC2s occur abundantly in peripheral tissues and arise from circulating blood cDC2s. However, the factors governing cDC2 differentiation in tissues, especially under inflammatory conditions, remained poorly defined.
Magdalena Lang, Corinna Krump, Anastasia Meshcheryakova, Carmen Tam-Amersdorfer, Elke Schwarzenberger, Christina Passegger, Sally Connolly, Diana Mechtcheriakova, Herbert Strobl   +8 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Escherichia coli cytolethal distending toxin blocks the HeLa cell cycle at the G2/M transition by preventing cdc2 protein kinase dephosphorylation and activation [PDF]

, 1997
Cytolethal distending toxins (CDT) constitute an emerging heterogeneous family of bacterial toxins whose common biological property is to inhibit the proliferation of cells in culture by blocking their cycle at G2/M phase.
Pérès, Sylvie Yvonne, Oswald, E., Comayras, C., de Rycke, Jean, Oswald, Eric, Comayras, Chrystel, Tasca, Christian, Rycke, Jean de, Ducommun, Bernard, Pérès, S.Y., Ducommun, B.   +10 more
core  

The effects of silver ions and silver nanoparticles on cell division and expression of cdc2 gene in Allium cepa root tips

Biologia Plantarum, 2018
The effects of silver nanoparticles (AgNPs), silver ions (Ag+), and polyvinylpyrrolidone (PVP) on mitosis and expression of a gene encoding cyclin-dependent kinase 2 (cdc2) in onion roots were compared.
A. S. Fouad, R. M. Hafez
doaj   +1 more source

Phosphorylation of caldesmon by cdc2 kinase.

Journal of Biological Chemistry, 1991
A recent report that mitosis-specific phosphorylation causes the nonmuscle caldesmon to dissociate from microfilaments (Yamashiro, S., Yamakita, Y., Ishikawa, R., and Matsumura, F. (1990) Nature 344, 675-678) suggests that this process may contribute to the major structural reorganization of the eukaryotic cell at mitosis.
A S, Mak, M H, Watson, C M, Litwin, J H, Wang   +3 more
openaire   +2 more sources

Carbodicarbene Monolayers on Au(111) Enable Strong Carbon(0)‐Metal Binding and Work‐Function Modulation

Small, EarlyView.
Carbodicarbene (CDC) molecules were utilized as surface ligands on Au(111) and showed higher thermal stability and work function modulation than N‐heterocyclic carbene (NHC). ABSTRACT Carbodicarbenes (CDCs), featuring a formally zero‐valent carbon atom coordinated by two N‐heterocyclic carbene (NHC) units, are exceptionally strong σ‐donor ligands in ...
Rajarshi Mondal, Joshua M. Sims, Soumyajit Rajak, Iris Berg, Shiraz Marigosian, Luca Schio, Masoumeh Alihosseini, Tzipora Ben‐Tzvi, Guido Fratesi, Luca Floreano, Nan Jiang, Carine Michel, Elad Gross   +12 more
wiley   +1 more source

J Subgroup Avian Leukosis Virus Strain Promotes Cell Proliferation by Negatively Regulating 14-3-3σ Expressions in Chicken Fibroblast Cells

Viruses, 2023
This study focuses on clarifying the regulation of chicken 14-3-3σ protein on the fibrous histiocyte proliferation caused by ALV-J-SD1005 strain infection.
Moyu Wang, Hongmei Li, Xiyu Sun, Jianhua Qiu, Changhua Jing, Huiyue Jia, Yujie Guo, Huijun Guo   +7 more
doaj   +1 more source