Results 71 to 80 of about 29,622 (230)

In VivoRegulation of Cyclin A/Cdc2 and Cyclin B/Cdc2 through Meiotic and Early Cleavage Cycles in Starfish

Developmental Biology, 1998
In starfish, fertilization occurs naturally at late meiosis I. In the absence of fertilization, however, oocytes complete meiosis I and II, resulting in mature eggs arrested at the pronucleus stage, which are still fertilizable. In this study, we isolated cDNAs of starfish cyclin A and Cdc2, and monitored extensively the cell cycle dynamics of cyclin A
Okano-Uchida, Takayuki, Sekiai, Tohru, Lee, Kyon-su, Okumura, Eiichi, Tachibana, Kazunori, Kishimoto, Takeo   +5 more
openaire   +2 more sources

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

Cell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo, Tianxiang Liu, Runling Ren, Na Li, Wenwen Zhang, Jingwen Si, Yongjun Piao, Yuanjing Hu   +7 more
wiley   +1 more source

Cdc2 exists in three forms with distinct phosphorylation levels.

, 2015
(A) Phosphorylation of S.pombe Cdc2 at threonine-14 (T14), tyrosine-15 (Y15) and threonine-167 (T167). Cdc2.1w is insensitive to inhibition by Wee1 kinase, whereas Cdc2.3w does not require activation by Cdc25 phosphatase. (B+C) Model of S.pombe Cdc2. The
Victoria Hilditch (763611), Thomas Caspari (155113)   +1 more
core   +1 more source

Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III

, 2002
The availability of a sister chromatid, and thus the cell cycle phase in which DNA double-strand breaks (DSBs) occur, influences the choice between homologous recombination (HR) or nonhomologous end joining (NHEJ).
Jo Murray (4460464), Thomas Caspari (155113), Antony Carr (4561024)   +2 more
core   +1 more source

Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses [Corrigendum]

Journal of Hepatocellular Carcinoma, 2023
Huang CY, Lai ZY, Hsu TJ, Chou FI, Liu HM, Chuang YJ. J Hepatocell Carcinoma. 2022;9:1385–1401. The authors have advised due to an error at the time of figure assembly, Figure 7A on page 1395 is incorrect.
Huang CY, Lai ZY, Hsu TJ, Chou FI, Liu HM, Chuang YJ   +5 more
doaj  

Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose

BMC Molecular and Cell Biology, 2019
Background Classic dendritic cells (cDCs) play a central role in the immune system by processing and presenting antigens to activate T cells, and consist of two major subsets: CD141+ cDC (cDC1) and CD1c+ cDC (cDC2).
Wenji Ma, Jaeyop Lee, Daniel Backenroth, Yu Jerry Zhou, Erin Bush, Peter Sims, Kang Liu, Yufeng Shen   +7 more
doaj   +1 more source

Wee1 kinase differentially regulates maize CDKA2;1a and CDKB1;1

The FEBS Journal, EarlyView.
In eukaryotes, Wee1 kinase inhibits the kinase activity of CDK/Cyc complexes through phosphorylation of a conserved residue in the CDK moiety. Wee1 is also present in plants, but has been scarcely studied. We have studied maize Wee1 regulation of CDKA/CycD2;2a or CDKB/CycD2;2a complexes.
Mingyar N. López‐Hernández, Estefany D. Guerrero‐Molina, Ulises Martínez‐Ortega, Aurora Lara‐Núñez, Jorge M. Vázquez‐Ramos   +4 more
wiley   +1 more source

S. mansoni -derived omega-1 prevents OVA-specific allergic airway inflammation via hampering of cDC2 migration.

PLoS Pathogens
Chronic infection with Schistosoma mansoni parasites is associated with reduced allergic sensitization in humans, while schistosome eggs protects against allergic airway inflammation (AAI) in mice.
Thiago A Patente, Thomas A Gasan, Maaike Scheenstra, Arifa Ozir-Fazalalikhan, Katja Obieglo, Sjoerd Schetters, Stijn Verwaerde, Karl Vergote, Frank Otto, Ruud H P Wilbers, Eline van Bloois, Yolanda van Wijck, Christian Taube, Hamida Hammad, Arjen Schots, Bart Everts, Maria Yazdanbakhsh, Bruno Guigas, Cornelis H Hokke, Hermelijn H Smits   +19 more
doaj   +1 more source

The Leukocyte Landscape Across Mouse Strains and Tissues

Immunology &Cell Biology, EarlyView.
The blood, bone marrow, liver, lymph nodes, and spleen of naïve male mice contained unique immunobiomes which differed between commonly used strains. BALB‐derived strains exhibited helper‐ and innate‐biased immune profiles, C57BL/6J‐derived strains were enriched for cytotoxic and immune surveillance populations, and DBA/2 J mice displayed elevated γδ T
Ella Trolio, Sarah Dart, Liu Liu, Michaela Lucas, Amy Prosser   +4 more
wiley   +1 more source

Phosphorylation by cdc2-CyclinB1 Kinase Releases Cytoplasmic Dynein from Membranes

, 2001
Movement of various cargoes toward microtubule minus ends is driven by the microtubule motor cytoplasmic dynein (CD). Many cargoes are motile only during certain cell cycle phases, suggesting that CD function may be under cell cycle control ...
Addinall, Stephen G., Mayr, Petra S., Sheehan, John K., Woodman, Philip G.; id_orcid, Allan, Victoria J., Doyle, Sandra   +5 more
core   +1 more source