Results 81 to 90 of about 29,622 (230)
Histiocytes: Multifaceted Regulators of Health and Disease
Veterinary Clinical Pathology, EarlyView.ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
Abi enhances Abl-mediated Cdc2 phosphorylation and inactivation
, 2008 [[abstract]]Abelson tyrosine kinase (Abl) is a non-receptor tyrosine kinase which is frequently coupled with adaptor proteins to interact with its substrates for the regulation of cytoskeleton rearrangement, cell growth and apoptosis in response to a ...
Lin, TY; Huang, CH; Chou, WG; Juang, JL
core +1 more source
Linker Histones Stimulate HSPA2 ATPase Activity Through NASP Binding and Inhibit CDC2/Cyclin B1 Complex Formation During Meiosis in the Mouse1 [PDF]
, 2009 In mammalian spermatocytes, cell division cycle protein 2 (CDC2)/cyclin B1 and the chaperone heat shock protein A2 (HSPA2) are required for the G2→M transition in prophase I.
O'Rand, Michael G. +5 more
core +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Inherited factors account for a large share of breast cancer susceptibility, yet the biological consequences of most risk variants are still poorly understood. To address this gap, we studied 175 breast cancer risk variants confirmed by genome‐wide association studies and gathered the genes that lie near them.
Sultana Jannat +11 more
wiley +1 more source
PLoS ONE, 2012 Lamins' functions are regulated by phosphorylation at specific sites but our understanding of the role of such modifications is practically limited to the function of cdc 2 (cdk1) kinase sites in depolymerization of the nuclear lamina during mitosis.
Magdalena Zaremba-Czogalla +5 more
doaj +1 more source
Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes
Journal of Applied Polymer Science, Volume 143, Issue 41, November 5, 2026.Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis +1 more
wiley +1 more source
The core network of events involving Cdc2/Cdc13, the selected substrates and their target genes.
, 2018 Shown are phosphorylation and regulation events involving the Cdc2/Cdc13 complex and the four selected substrates (transcription factors—yellow triangles) with their target genes that feed back onto Cdc2/Cdc13.
Dania Humaidan (6041318) +2 more
core +1 more source
Advanced Materials, Volume 38, Issue 56, 8 October 2026.A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte +21 more
wiley +1 more source
Investigation of CDC2-independent mitotic protein kinases
, 1997 Mitosis is a highly coordinated event which ensures the equal segregation of the cytoplasmic and genetic material into two daughter cells. A key regulatory process in ensuring the temporal fidelity of mitosis involves reversible protein phosphorylation
Gowdy, Patrick Michael
core +1 more source