Results 41 to 50 of about 531,349 (289)
Activation of type‐1 protein phosphatase by cdc2 kinase [PDF]
FEBS Letters, 1992 Purified cdc2 or cdc2 obtained from HeLa cells in association with p131sucl activate inactive type‐1 protein phosphatase (PP1) (catalytic subunit · inhibitor‐2 complex, purified from skeletal muscle). Likewise in the case of PP1 activation by FA/GSK3, activation by cdc2 is accompanied by phosphorylation of inhibitor‐2 (I2) and free I2 can be ...
openaire +3 more sources
Tumor Biology, 2017 Fibroblast growth factor 8b and androgen play important roles in cell proliferation of prostate cancer. We investigated the effects of fibroblast growth factor 8b and androgen on the proliferation of prostate cell lines and the corresponding ...
Wen-jun Xiao +2 more
doaj +1 more source
Journal of Pharmacopuncture, 2019 DNA: Deoxyribonucleic acid, BRCA1: Breast cancer gene 1, BRCA2: Breast cancer gene 2,WHO: World Health Organization, Nrf2: Nuclear factor erythroid 2 [NF-E2]-related factor 2 , NF-κB: Nuclear factor kappa-light-chain-enhancer of activated B cells, MDR ...
Mahavir H. Ghante, Prasad G. Jamkhande
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Zinc regulates meiotic resumption in porcine oocytes via a protein kinase C-related pathway. [PDF]
PLoS ONE, 2014 Zinc is an extremely important trace element that plays important roles in several biological processes. However, the function of zinc in meiotic division of porcine oocytes is unknown.
Ming-Hui Zhao +7 more
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Checkpoint-Dependent Regulation of Origin Firing and Replication Fork Movement in Response to DNA Damage in Fission Yeast [PDF]
, 2009 To elucidate the checkpoint mechanism responsible for slowing passage through S phase when fission yeast cells are treated with the DNA-damaging agent methyl methanesulfonate (MMS), we carried out two-dimensional gel analyses of replication intermediates
Huberman, Joel A., Kumar, Sanjay
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Cell Division, 2009 Chk1 is a serine/threonine protein kinase that is the effector of the G2 DNA damage checkpoint. Chk1 homologs have a highly conserved N-terminal kinase domain, and a less conserved C-terminal regulatory domain of ~200 residues.
Calonge Teresa M +2 more
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Two Cdc2 Kinase Genes with Distinct Functions in Vegetative and Infectious Hyphae in Fusarium graminearum. [PDF]
PLoS Pathogens, 2015 Eukaryotic cell cycle involves a number of protein kinases important for the onset and progression through mitosis, most of which are well characterized in the budding and fission yeasts and conserved in other fungi.
Huiquan Liu +7 more
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Resolving the binding-kinase discrepancy in bacterial chemotaxis: A nonequilibrium allosteric model and the role of energy dissipation [PDF]
Proc. Natl. Acad. Sci. U.S.A. 120, e2303115120 (2023), 2023 The Escherichia coli chemotaxis signaling pathway has served as a model system for studying the adaptive sensing of environmental signals by large protein complexes. The chemoreceptors control the kinase activity of CheA in response to the extracellular ligand concentration and adapt across a wide concentration range by undergoing methylation and ...
arxiv +1 more source
Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimer's disease [PDF]
, 2005 We have recently reported that a polymorphism in the cell division cycle (CDC2) gene, designated Ex6 + 7I/D, is associated with Alzheimer's disease (AD). The CDC2 gene is located on chromosome 10q21.1 close to the marker D10S1225 linked to AD.
Andreasen N +42 more
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Comparative analysis of two murine CDC25B isoforms [PDF]
Archives of Biological Sciences, 2017 CDC25B phosphatase plays a pivotal role in the cell cycle process by dephosphorylating and activating the CDC2 kinase of maturation-promoting factor (MPF). In mice, two transcripts of Cdc25B are generated by the alternative splicing of one gene.
Kang Min Kook +3 more
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