Results 161 to 170 of about 125,522 (281)

41P Dual inhibition of PLK1 and multi-CDKs: A novel approach for the treatment of adrenocortical carcinomas [PDF]

open access: gold
Emanuela Esposito   +9 more
openalex   +1 more source

Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence

open access: yesCancer Innovation, Volume 5, Issue 1, February 2026.
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley   +1 more source

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa   +4 more
wiley   +1 more source

CDK Literature #4

open access: yes, 2008
Fourth in the CDK Literature series. Really, a follow up on #3 which I wanted to get out, even though not really finished yet. But, after 3 comes 4, not 3b. Maybe 3.1, but that suggests at least 3.2-3.9 too, let alone full R (that was supposed to the space of all reals…) I'll stick to positive non-zero integers. #1 and #2 are still available too.
openaire   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy   +4 more
wiley   +1 more source

Podocyte expression of the CDK-inhibitor p57 during development and disease [PDF]

open access: bronze, 2001
Keiju Hiromura   +8 more
openalex   +1 more source

Engineering Immortalized Bovine Granulosa Cells Using a Triple‐Gene Approach: Mutant CDK4, Cyclin D1, and TERT

open access: yesCell Biology International, Volume 50, Issue 2, February 2026.
ABSTRACT Advancing reproductive technologies in livestock is essential to improve both productivity and genetic potential of cattle. Despite this importance, application of reproductive biotechnologies in cattle breeding remains limited. Bovine granulosa cells (bGCs), which are key components of the ovarian follicle, are critical in female reproduction
Lanlan Bai   +12 more
wiley   +1 more source

Updating Ruby CDK

open access: yes, 2009
It’s been over two years since Ruby CDK was first announced. For the unfamiliar, Ruby CDK offers a convenient way to use the Chemistry Development Kit from the MRI Ruby implementation. Over the least several months, I’ve received quite a few emails about Ruby CDK.
openaire   +1 more source

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