Results 161 to 170 of about 72,520 (322)

Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura, Yuki Murakami, Yusuke Oshima, Takashi Masuda, Wataru Miyoshino, Hiroomi Takayama, Yoko Kawano, Teijiro Hirashita, Yuichi Endo, Masafumi Inomata   +9 more
wiley   +1 more source

CDK1 Inactivation Regulates Anaphase Spindle Dynamics and Cytokinesis In Vivo [PDF]

, 1997
Sally P. Wheatley, Edward H. Hinchcliffe, Michael Glotzer, Anthony A. Hyman, Greenfield Sluder, Yu-Li Wang   +5 more
openalex   +1 more source

Cell adhesion is regulated by CDK1 during the cell cycle

Journal of Cell Biology, 2018
In most tissues, anchorage-dependent growth and cell cycle progression are dependent on cells engaging extracellular matrices (ECMs) via integrin–receptor adhesion complexes.
Matthew C. Jones, J. Askari, J. Humphries, M. Humphries   +3 more
semanticscholar   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Chk1–cyclin A/Cdk1 axis regulates origin firing programs in mammals [PDF]

, 2009
Makoto Nakanishi, Yuko Katsuno, Hiroyuki Niida, Hiroshi Murakami, Midori Shimada   +4 more
openalex   +1 more source

Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade. [PDF]

, 2020
Saturated fatty acids (SFAs) (the "bad" fat), especially palmitate (PA), in the human diet are blamed for potential health risks such as obesity and cancer because of SFA-induced lipotoxicity. However, epidemiological results demonstrate a latent benefit
Candas-Green, Demet, Chen, Hong-Wu, Fan, Ming, Hu, Yiyang, Jiang, Joy X, Li, Jian Jian, Liu, Lin, Wang, Yinsheng, Wei, Ryan, Xie, Bowen   +9 more
core  

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

HAND2-AS1 plays a tumor-suppressive role in hepatoblastoma through the negative regulation of CDK1

Heliyon
Objective: Hepatoblastoma (HB) is the most commonly seen pediatric liver malignancy. The preliminary experiment of our research group found that cyclin dependent kinase 1 (CDK1) was upregulated in HB.
Keke Chen, Yalan You, Wenfang Tang, Xin Tian, Chengguang Zhu, Zexi Yin, Minhui Zeng, Xiangling He   +7 more
doaj   +1 more source

Cyclin dependent kinase 1 (CDK1) positively regulates cardiac hypertrophy and fibrosis via TGF-beta pathway [PDF]

, 2020
Tomoko Yamamoto, Shouji Matsushima, Kazuto Okabe, S Ikeda, Akihito Ishikita, Nobuyuki Enzan, Masashi Sada, Yoshitomo Tsutsui, Ryo Miyake, Hiroyuki Tsutsui   +9 more
openalex   +1 more source

Bioinformatics Analysis Reveals CDK1 and DLGAP5 as Key Modulators of Tumor Immune Cell Infiltration in Hepatocellular Carcinoma

Cancer Management and Research
Jiajing Li,1 Qi Liu,2 Ting Zhang,2 Qian Du3 1The Diagnostics Laboratory, Affiliated Hospital to Zunyi Medical University, Zunyi, Guizhou, 563000, People’s Republic of China; 2Affiliated Hospital to Zunyi Medical University, Zunyi, Guizhou, 563000, People’
Li J, Liu Q, Zhang T, Du Q
doaj