Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling [PDF]
, 2005 Christian Preisinger +5 more
openalex +1 more source
Exploring the Single‐Cell Dynamics of FOXM1 Under Cell Cycle Perturbations
Cell Proliferation, EarlyView.The varied FOXM1 dynamic patterns reveal significant differences in cellular responses to the same stimuli at the single‐cell level. This emphasises the relationship between cue, signal and response as influenced by different drug types and concentrations.
Tooba Jawwad +6 more
wiley +1 more source
The Cdk1 Complex Plays a Prime Role in Regulating N-Myc Phosphorylation and Turnover in Neural Precursors [PDF]
, 2005 Sarah K. Sjostrom +4 more
openalex +1 more source
Deficiency of Aging‐Related Gene Chitinase‐Like 4 Impairs Olfactory Epithelium Homeostasis
Cell Proliferation, EarlyView.Deficiency of Chil4 impairs OE homeostasis through loss of sustentacular cells and a specific type of immature sensory neuron, cell cycle arrest in globose basal cells, and inflammatory activation in microglia‐like cells. ABSTRACT Mammalian olfactory epithelium (OE) undergoes consistent self‐renewal throughout life.
Tingting Wu +7 more
wiley +1 more source
Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]
, 2005 Tomoya Yamaguchi +9 more
openalex +1 more source
Tumour Cell Size Control and Its Impact on Tumour Cell Function
Cell Proliferation, EarlyView.The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley +1 more source
HAND2-AS1 plays a tumor-suppressive role in hepatoblastoma through the negative regulation of CDK1
HeliyonObjective: Hepatoblastoma (HB) is the most commonly seen pediatric liver malignancy. The preliminary experiment of our research group found that cyclin dependent kinase 1 (CDK1) was upregulated in HB.
Keke Chen +7 more
doaj
Cell Proliferation, EarlyView.The micropeptide altH19 interacts with phosphorylated CDK2 (p‐CDK2), subsequently activating CDK2 phosphorylation. This enhances the downstream E2F1 target gene RB activity, which accelerates DNA replication, ultimately leading to rapid myeloma cell mitosis and proliferation.
Yaxin Zhang +6 more
wiley +1 more source
Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): Overexpression of NPM, CDK1 and NDRG1 and underexpression of CHES1 [PDF]
, 2005 Joseph Tung‐Chieh Chang +10 more
openalex +1 more source
Cell Proliferation, EarlyView.Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao +7 more
wiley +1 more source