Results 101 to 110 of about 28,778 (201)

ins(9;4)(q33;q12q25) [PDF]

open access: yes, 2010
Review on ins(9;4)(q33;q12q25), with data on clinics, and the genes ...
Huret, JL
core   +1 more source

Whispers of Growth: The Impact of MicroRNA on the Proliferation Potential of Adipose‐Derived Stem Cells—A Review

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Adipose‐derived stem cells (ADSCs) have garnered significant interest in regenerative medicine (RM) due to their abundant availability, ease of isolation, and ability to differentiate into various cell types. The growth of ADSCs is crucial for their therapeutic effectiveness, as it directly influences their ability to repair damaged tissues. MicroRNAs (
Maryam Bahrami   +4 more
wiley   +1 more source

Regulation of Mitochondrial Dynamics and Neurodegenerative Diseases [PDF]

open access: yes, 2011
Mitochondria are important cellular organelles in most metabolic processes and have a highly dynamic nature, undergoing frequent fission and fusion. The dynamic balance between fission and fusion plays critical roles in mitochondrial functions. In recent
Fujimura, Atsushi   +6 more
core   +1 more source

Mitochondria‐Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen   +14 more
wiley   +1 more source

Cell-Penetrating Fragments of the Cdk5 Regulatory Subunit Are Protective in Models of Neurodegeneration

open access: yesPharmaceuticals, 2010
Cdk5 is essential for neuronal differentiation processes in the brain. Activation of Cdk5 requires the association with the mostly neuron-specific p35 or p39.
Jan Liman   +3 more
doaj   +1 more source

RBR E3 ubiquitin ligases: new structures, new insights, new questions [PDF]

open access: yes, 2014
The RBR (RING-BetweenRING-RING) or TRIAD [two RING fingers and a DRIL (double RING finger linked)] E3 ubiquitin ligases comprise a group of 12 complex multidomain enzymes.
Shaw, Gary S.   +2 more
core   +1 more source

Differential expression of cyclin-dependent kinases in the adult human retina in relation to CDK inhibitor retinotoxicity [PDF]

open access: yes, 2019
Cyclin-dependent kinases (CDKs) are a family of kinases associated predominantly with cell cycle control, making CDK inhibitors interesting candidates for anti-cancer therapeutics.
Healing, Guy   +3 more
core   +1 more source

Stress-Induced CDK5 Activation Disrupts Axonal Transport via Lis1/Ndel1/Dynein

open access: yesCell Reports, 2015
Axonal transport is essential for neuronal function, and defects in transport are associated with multiple neurodegenerative diseases. Aberrant cyclin-dependent kinase 5 (CDK5) activity, driven by the stress-induced activator p25, also is observed in ...
Eva Klinman, Erika L.F. Holzbaur
doaj   +1 more source

Cyclin Dependent Kinase 5 in Endothelial Cell Migration [PDF]

open access: yes, 2010
Cyclin dependent kinase 5 (Cdk5) is studied to take part in the migration neurons and development of brain. It is proven to participate also in the mediation of endothelial cell migration and angiogenesis.
Heiskanen, Suvi
core  

Cdk5 protects huntingtin

open access: yesThe Journal of Cell Biology, 2005
![Graphic][1] Cdk5 (red) phosphorylates htt (green) and protects it from caspases.A cyclin-dependent kinase protects neurons from toxic fragments of huntingtin (htt), according to Luo et al.
openaire   +2 more sources

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