Results 171 to 180 of about 61,476 (246)

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Comprehensive Analysis of Cuproptosis-Related Genes According to Cancer Stage and Their Prognostic Value in Cervical Cancer. [PDF]

Int J Mol Sci
He J, Sun Y, Yang Z, Xu D, Zhang P, Xia J.   +5 more
europepmc   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

Contrasting molecular and pharmacodynamic signatures of response and resistance to sequential bortezomib and temozolomide in recurrent IDH-wildtype glioblastoma and grade 4 IDH-mutant astrocytoma: an exploratory interim analysis of NCT03643549 phase IB/II trial. [PDF]

Biomark Res
Goplen D, Rahman MA, Brekke J, Waha A, Oltedal L, Haasz J, Kumar S, Birkeland E, Selheim F, Lie SA, Chekenya M.   +10 more
europepmc   +1 more source

Biological Biomarkers in Proliferative Verrucous Leukoplakia: A Systematic Review and Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Objective To synthesise biological biomarker evidence in proliferative verrucous leukoplakia/proliferative leukoplakia and quantify malignant transformation using eligible longitudinal evidence. Methods Primary human biomarker studies and longitudinal studies reporting extractable malignant‐transformation events and denominators were ...
Madawi Faisal Alkeheli, Hisham I. Othman
wiley   +1 more source

Familial melanoma: genetic, clinical, and dermoscopic insights and follow-up. [PDF]

Front Med (Lausanne)
Raika AE, de Las Heras Alonso ME, Sproge D, Bataraga E.   +3 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Case Report WIN-MTB-2024001 - WIN International Molecular Tumor Board: A 55-year-old male with glioblastoma exhibiting amplifications in MDM2 and EGFR. [PDF]

Oncotarget
El-Deiry WS, Ikeda S, Magidi S, Bresson C, Abdel-Razeq H, Joshua A, Hernando-Calvo A, Oberoi A, Hu Z, Meissner T, Elsey R, Al-Omari A, Wunder F, Kurzrock R.   +13 more
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Metabolic-cell-death gene trio predicts survival and cuproptosis sensitivity in colorectal cancer. [PDF]

J Gastrointest Oncol
Zhuang W, Zhang Y, Liu Z, Yan W, Wei T, Deng Q, Liu Q.   +6 more
europepmc   +1 more source