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Journal of Allergy and Clinical Immunology, 2019 Celiac disease is a common form of enteropathy with frequent extraintestinal manifestations (EIM). Misrecognition of these presentations may lead to significant delays in diagnosis.
A. Therrien, C. Kelly, J. Silvester
semanticscholar +6 more sources
Gastroenterology Research and Practice, 2012 Celiac disease is common, affecting approximately 1 in 100 people, yet it remains underdiagnosed. This article reviews our current understanding of celiac disease, diagnosis, and common pitfalls. Although the cornerstone of treatment is a gluten-free diet, some patients may still have persisting symptoms and warrant further investigations.
Makharia, G.K. +3 more
+12 more sources
Oral Diseases, 2013 Celiac disease, with a prevalence around 1% of the general population, is the most common genetically‐induced food intolerance in the world. Triggered by the ingestion of gluten in genetically predisposed individuals, this enteropathy may appear at any age, and is characterized by a wide variety of clinical signs and symptoms.
Stefano Guandalini +3 more
openaire +6 more sources
Canadian Journal of Gastroenterology, 2000 Increased awareness of the high prevalence of celiac disease and the degree of underdiagnosis has led to calls for routine screening in certain groups. The potential consequences of underdiagnosis have been the subject of several studies. Where there is a delay in diagnosis, there may be an increased risk of associated autoimmune diseases ...
King, A L, Ciclitira, P J
openaire +6 more sources
BMJ Open Gastroenterology, 2022 Objective To investigate the prevalence and associated factors of persistent symptoms despite a strict gluten-free diet in adult patients with coeliac disease diagnosed in childhood.Design Medical data on 239 currently adult patients with paediatric ...
Katri Kaukinen +6 more
doaj +1 more source
Missing Insight Into T and B Cell Responses in Dermatitis Herpetiformis
Frontiers in Immunology, 2021 Dermatitis herpetiformis is a cutaneous form of celiac disease manifesting as an itching rash typically on the elbows, knees and buttocks. It is driven by the ingestion of gluten-containing cereals and characterized by granular deposits of immunoglobulin
Esko Kemppainen +3 more
doaj +1 more source
A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease.
New England Journal of Medicine, 2021 BACKGROUND In celiac disease, small intestinal transglutaminase 2 causes deamidation of glutamine residues in gluten peptides, which enhances stimulation of T cells and leads to mucosal injury.
D. Schuppan +25 more
semanticscholar +1 more source
Frontiers in Nutrition, 2021 Disturbances of the gut microbiota may influence the development of various autoimmune diseases. This study investigated the effects of supplementations with the probiotic bacteria, Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei ...
Elin Oscarsson +4 more
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Epidemiology, Presentation, and Diagnosis of Celiac Disease.
Gastroenterology, 2020 The incidence of celiac disease is increasing, partly due to improved recognition of, and testing for, the disease. The rise in incidence is also due to a real increase of this immune-based disorder, independent of disease detection. The reasons for this
B. Lebwohl, A. Rubio-Tapia
semanticscholar +1 more source
Frontiers in Nutrition, 2021 Updated information on child feeding practices, nutritional status, and trends related to parental sociodemographic variables is required in developing countries.
Adugna Negussie Gudeta +3 more
doaj +1 more source