Results 31 to 40 of about 9,466,106 (302)

Haptoglobin Polymorphism: A Novel Genetic Risk Factor for Celiac Disease Development and Its Clinical Manifestations [PDF]

, 2008
Background: Haptoglobin (Hp) α-chain alleles 1 and 2 account for 3 phenotypes that may influence the course of inflammatory diseases via biologically important differences in their antioxidant, scavenging, and immunomodulatory properties.
Altorjay, István, Barta, Zsolt, Dinya, T., Földi, I., Gyetvai, A., Hársfalvi, Jolán, Kapitany, A., Korponay-Szabó, Ilma Rita, Lakatos, Péter László, Mate, I., Nemes, E., Papp, Mária, Szathmari, E., Toth, L., Tumpek, J., Udvardy, M., Varvolgyi, C., Veres, Gábor   +17 more
core   +1 more source

Association Between Celiac Disease and Mortality Risk in a Swedish Population.

Journal of the American Medical Association (JAMA), 2020
Importance Celiac disease may be associated with a modest but persistent increased long-term mortality risk. It is uncertain whether this risk has changed in the era of wider diagnosis rates, less severe clinical disease, and more widespread availability
B. Lebwohl, P. Green, J. Söderling, B. Roelstraete, J. Ludvigsson   +4 more
semanticscholar   +1 more source

Transcriptome Analysis of CD4+ T Cells in Coeliac Disease Reveals Imprint of BACH2 and IFNγ Regulation [PDF]

, 2015
peer-reviewedData Availability: The raw sequencing reads (FASTQ files) and sequence read counts mapped to UCSC hg19 for each of the 74 transcriptomes sequenced in this study have been deposited at Gene Expression Omnibus (GEO) accession GSE69549.This ...
Castro, Patricia Dominguez, Coleman, Ciara, Cormican, Paul, Mahmud, Nasir, McManus, Ross, Molloy, Ben, Quinn, Emma M, Trimble, Valerie   +7 more
core   +17 more sources

Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation

Science Translational Medicine, 2020
Impaired AhR ligand production by the gut microbiota decreases AhR pathway activation, promoting inflammation in celiac disease. The advantage of a high-tryptophan diet Although 40% of the worldwide population express celiac disease susceptibility genes,
B. Lamas, Leticia Hernández-Galán, H. Galipeau, M. Constante, A. Clarizio, J. Jury, N. Breyner, A. Caminero, G. Rueda, Christina L. Hayes, Justin L. McCarville, Miriam Bermúdez Brito, J. Planchais, N. Rolhion, J. Murray, P. Langella, L. Loonen, J. Wells, P. Bercik, H. Sokol, E. Verdú   +20 more
semanticscholar   +1 more source

Intestinal Barrier Function in Gluten-Related Disorders [PDF]

, 2019
Gluten-related disorders include distinct disease entities, namely celiac disease, wheat-associated allergy and non-celiac gluten/wheat sensitivity. Despite having in common the contact of the gastrointestinal mucosa with components of wheat and other ...
Branchi, Federica, Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Moerkens, Renée, Schumann, Michael, Withoff, Sebo   +6 more
core   +2 more sources

Celiac disease: a comprehensive current review

BMC Medicine, 2019
BackgroundCeliac disease remains a challenging condition because of a steady increase in knowledge tackling its pathophysiology, diagnosis, management, and possible therapeutic options.Main bodyA major milestone in the history of celiac disease was the ...
Giacomo Caio, U. Volta, A. Sapone, D. Leffler, R. De Giorgio, C. Catassi, A. Fasano   +6 more
semanticscholar   +1 more source

Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease.

Gastroenterology, 2020
BACKGROUND & AIMS Celiac disease could be treated, and potentially cured, by restoring T-cell tolerance to gliadin. We investigated the safety and efficacy of negatively charged, 500 nm, poly(lactide-co-glycolide) nanoparticles encapsulating gliadin ...
T. Freitag, Joseph R. Podojil, Ryan M. Pearson, F. Fokta, C. Sahl, Marcel Messing, L. Andersson, K. Leskinen, P. Saavalainen, Lisa I. Hoover, Kelly Huang, D. Phippard, S. Maleki, N. King, L. Shea, S. Miller, S. Meri, D. Getts   +17 more
semanticscholar   +1 more source

Small-intestinal TG2-specific plasma cells at different stages of coeliac disease

BMC Immunology, 2018
Background In coeliac disease, ingestion of gluten induces the production of transglutaminase 2 (TG2)-targeted autoantibodies by TG2-specific plasma cells present at high frequency in the small intestinal mucosa in untreated disease.
Minna Hietikko, Outi Koskinen, Kalle Kurppa, Kaija Laurila, Päivi Saavalainen, Teea Salmi, Tuire Ilus, Heini Huhtala, Katri Kaukinen, Katri Lindfors   +9 more
doaj   +1 more source

Innate Lymphoid Cells and Celiac Disease: Current PerspectiveSummary

Cellular and Molecular Gastroenterology and Hepatology, 2021
Celiac disease (CD) is a common autoimmune disorder triggered by the ingestion of gluten in genetically susceptible individuals. Although the mechanisms underlying gliadin-mediated activation of adaptive immunity in CD have been well-characterized ...
Xuechen Yu, Justin Vargas, Peter H.R. Green, Govind Bhagat   +3 more
doaj   +1 more source

Anesthesia experience along with familial Mediterranean fever and celiac disease [PDF]

, 2014
(Anesthetic management in patient with Familial Mediterranean Fever and Celiac Disease) Familial Mediterranean Fever is an autosomal recessive transmitted disease which often seen at Mediterranean origin society and it goes by deterioration at ...
Gülçin Hacıbeyoğlu, Hale Borazan, Mehmet Sargın, Şeref Otelcioğlu   +3 more
core   +1 more source