Results 71 to 80 of about 23,965 (251)

Cultured meat with enriched organoleptic properties by regulating cell differentiation

Nature Communications
Research on cultured meat has primarily focused on the mass proliferation or differentiation of muscle cells; thus, the food characteristics of cultured meat remain relatively underexplored.
Milae Lee, Sohyeon Park, Bumgyu Choi, Woojin Choi, Hyun Lee, Jeong Min Lee, Seung Tae Lee, Ki Hyun Yoo, Dongoh Han, Geul Bang, Heeyoun Hwang, Won-Gun Koh, Sangmin Lee, Jinkee Hong   +13 more
doaj   +1 more source

Methods to Isolate Muscle Stem Cells for Cell-Based Cultured Meat Production: A Review

Animals
Cultured meat production relies on various cell types, including muscle stem cells (MuSCs), embryonic stem cell lines, induced pluripotent cell lines, and naturally immortalized cell lines.
Jae-Hoon Lee, Tae-Kyung Kim, Min-Cheol Kang, Minkyung Park, Yun-Sang Choi   +4 more
doaj   +1 more source

Safety Issues in the Development of Cell-Cultured Meat

Highlights in Science, Engineering and Technology
Currently, traditional animal husbandry faces problems such as low utilization of land resources, abuse of antibiotics, and excessive carbon emissions caused by animal husbandry. Therefore, the effectiveness of a new industry to replace traditional animal husbandry has become the main research topic at this stage.
openaire   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

Advanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling, Ayşe Tuğçe Şahin, Bernardo Miller Naranjo, Stefano Aime, Doris Roth, Anna Pukaluk, Niels Tepho, Romina Augustin, Benedetta Zampa, Andrea S. Vendrame, Mark‐Christian Klassen, Ellen Emken, Marion Kiechle, Mircea Gabriel Stoleriu, Pontus Mertsch, Ruth Olmer, Yohannes Tesfaigzi, Oliver Lieleg, Janna C. Nawroth   +18 more
wiley   +1 more source

The Sustainable Development Issues of Animal Cell-cultured Meat

Highlights in Science, Engineering and Technology
As an innovative technology for alternative protein production, cell-cultured meat faces various sustainability challenges in terms of environment, economy and society. This paper systematically reviews its production processes (including cell acquisition and selection, scale production, cell differentiation and tissue formation) Analyses show that ...
Wanting Xu, Jinkai Yang, Zhe Yu
openaire   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Establishment of chicken muscle and adipogenic cell cultures for cultivated meat production

Frontiers in Nutrition
Abstract Cultured meat aims to replicate the sensory and functional properties of conventional meat by developing structured muscle tissue using cell culture. This study focuses on the culture of chicken embryonic and mesenchymal stem cells (MSCs) to derive muscle, and fat, optimizing conditions for differentiation ...
Vanessa Haach, Karine R. D. Silveira, Maíra de A. Peixoto, Ana Paula P. Sá, Vanessa Gressler, Vivian Feddern, Adriana M. G. Ibelli, Luciano Paulino Silva, Ana Paula Bastos   +8 more
openaire   +3 more sources

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

Advanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko, Dongyoon Shin, Junho Park, June Huh, Youngsoo Kim, Jong‐Wan Park   +5 more
wiley   +1 more source

Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer

Advanced Science, EarlyView.
SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han, Tian‐Yuan Tan, Bin Zhang, Ye‐Bin Fu, Wen Chen, Min‐Hui Yang, Yi‐Qing Wang, Yan‐Qing Ding, Shuang Wang   +8 more
wiley   +1 more source