Results 71 to 80 of about 30,394 (278)

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

Advanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang, Yadong Yang, Yongsheng Wang, Guirui Yu   +3 more
wiley   +1 more source

Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method

Advanced Science, EarlyView.
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas, Daniëlle C. A. Duffhues, Pim van den Bersselaar, Sarah Pragnere, Bart G. W. Groenen, Mariana Azevedo Gonzalez Oliva, Giuseppe Ciccone, Manuel Salmeron‐Sanchez, Carlijn V. C. Bouten, Jose J. Muñoz, Vito Conte   +10 more
wiley   +1 more source

Bioprocess Design Considerations for Cultured Meat Production With a Focus on the Expansion Bioreactor

, 2019
Cultured meat, as a cellular agriculture product, utilizes tissue engineering techniques and consequently faces not only cell culture challenges but also scale-up limitations. To ensure cultured meat is financially viable, efficient bioprocess design for
Allan, Scott J., De Bank, Paul A., Ellis, Marianne J.   +2 more
core   +1 more source

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

Establishment of two continuous adult stem cell lines from muscle and adipose tissues of rainbow trout (Oncorhynchus mykiss) for marbled fish meat production

Aquaculture Reports
Cell-cultured meat is an emerging technology with the potential to meet the nutritional needs, reduce environmental pollution and promote animal welfare.
Yaru Li, Ting Xue, Song Wang, Yue Zhang, Guoxiang Luan, Jinwu Wang, Huarong Guo   +6 more
doaj   +1 more source

Scaffolding Biomaterials for 3D Cultivated Meat: Prospects and Challenges

Advanced Science, 2022
Cultivating meat from stem cells rather than by raising animals is a promising solution to concerns about the negative externalities of meat production.
Claire Bomkamp, Stacey C. Skaalure, Gonçalo F. Fernando, Tom Ben‐Arye, Elliot W. Swartz, Elizabeth A. Specht   +5 more
doaj   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Establishment of chicken muscle and adipogenic cell cultures for cultivated meat production

Frontiers in Nutrition
Abstract Cultured meat aims to replicate the sensory and functional properties of conventional meat by developing structured muscle tissue using cell culture. This study focuses on the culture of chicken embryonic and mesenchymal stem cells (MSCs) to derive muscle, and fat, optimizing conditions for differentiation ...
Vanessa Haach, Karine R. D. Silveira, Maíra de A. Peixoto, Ana Paula P. Sá, Vanessa Gressler, Vivian Feddern, Adriana M. G. Ibelli, Luciano Paulino Silva, Ana Paula Bastos   +8 more
openaire   +3 more sources