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Phenotypes from cell-free DNA [PDF]
Open Biology, 2020 Cell-free DNA (cfDNA) has the potential to enable non-invasive detection of disease states and progression. Beyond its sequence, cfDNA also represents the nucleosomal landscape of cell(s)-of-origin and captures the dynamics of the epigenome.
Alexis Zukowski +2 more
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Immunoregulatory properties of cell free DNA [PDF]
Cellular and Molecular Life SciencesCell free DNA (cfDNA) is detectable at low concentrations in the plasma of healthy subjects and at high concentrations in disorders characterized by a high rate of necrotic events, such as tumors and vasculitis, leading to the release of necrotic DNA ...
Francesca Ferrera +20 more
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Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders [PDF]
Advanced ScienceInflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs. Cell‐free DNA (cfDNA) is not only a biomarker for various inflammatory diseases, but also a driver in innate immune responses, offering ...
Jiatong Li +7 more
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Cell-free circulating tumor DNA in cancer [PDF]
Chinese Journal of Cancer, 2016 Cancer is a common cause of death worldwide. Despite significant advances in cancer treatments, the morbidity and mortality are still enormous. Tumor heterogeneity, especially intratumoral heterogeneity, is a significant reason underlying difficulties in
Zhen Qin +4 more
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Circulating cell-free DNA biomarkers
APIK Journal of Internal Medicine, 2021 Jose Rafael Villarreal Escorcia
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Cell-free DNA screening in twin pregnancies [PDF]
Obstetrics & Gynecology ScienceCell-free DNA (cfDNA) screening for fetal aneuploidies is clinically available and exhibits better performance than conventional serum screening tests. However, data on the clinical performance of cfDNA screening in twin pregnancies are limited.
Hye Yeon Boo, You Jung Han
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Cell-Free DNA in Rheumatoid Arthritis [PDF]
International Journal of Molecular Sciences, 2021 Endogenous DNA derived from the nuclei or mitochondria is released into the bloodstream following cell damage or death. Extracellular DNA, called cell-free DNA (cfDNA), is associated with various pathological conditions. Recently, multiple aspects of cfDNA have been assessed, including cfDNA levels, integrity, methylation, and mutations.
Hashimoto, Teppei +3 more
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Cell-free fetal DNA and cell-free total DNA levels in spontaneous abortion with fetal chromosomal aneuploidy. [PDF]
PLoS ONE, 2013 Cell-free fetal DNA and cell-free total DNA in maternal circulation have been proposed as potential markers for noninvasive monitoring of the placental condition during the pregnancy. However, the correlation of and change in cell-free fetal DNA and cell-
Ji Hyae Lim +7 more
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Isolation and Quantification of Plasma Cell-Free DNA Using Different Manual and Automated Methods
Diagnostics, 2022 Plasma cell-free DNA (cfDNA) originates from various tissues and cell types and can enable minimally invasive diagnosis, treatment and monitoring of cancer and other diseases.
Eleni Polatoglou +4 more
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