Results 161 to 170 of about 1,636,041 (314)

Exploring the Utility of Cell-Free DNA Hydroxymethylation Profiling in Small-Cell Lung Cancer. [PDF]

Int J Mol Sci
Li JJN, Cheng D, Zhan LJ, Sacdalan DB, Ul Haq S, Singhawansa A, Philip V, Leighl NB, Bratman SV, Liu G, Lok BH.   +10 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Cell-Free DNA Uncovered Tumor Heterogeneity and Informed Targeted Therapy in a Pediatric Rhabdomyosarcoma. [PDF]

JCO Precis Oncol
Faucher J, Richer C, Langlois S, Rouette A, Bianco S, Sontag T, Lepage MÈ, Da Silva E, Cellot S, Tran TH, Parbhoo K, Cottrell CE, Sinnett D, Michon B, Lavallée VP, Santiago R.   +15 more
europepmc   +1 more source

Development and Application of Duplex Sequencing Strategy for Cell-Free DNA–Based Longitudinal Monitoring of Stage IV Colorectal Cancer

, 2019
Saradhi Mallampati, Stephanie Zalles, Dzifa Y. Duose, Peter Hu, L. Jeffrey Medeiros, Ignacio I. Wistuba, Scott Kopetz, Rajyalakshmi Luthra   +7 more
openalex   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Cancer-Like Fragmentomic Characteristics of Somatic Variants in Cell-Free DNA. [PDF]

Adv Sci (Weinh)
Zhang Z, An Y, Yang M, Pan Y, Liu X, Gong F, Lin H, Tang B, Bai Y, Zhao X, Zhao Y, Du C, Sun K.   +12 more
europepmc   +1 more source

An Economic Analysis of Cell-Free DNA Non-Invasive Prenatal Testing in the US General Pregnancy Population

, 2015
Peter Benn, Kirsten J. Curnow, Steven H. Chapman, Steven N. Michalopoulos, John Hornberger, Matthew Rabinowitz   +5 more
openalex   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Donor-derived Cell-free DNA for Detection of Rejection After Pancreas Transplantation. [PDF]

Transplant Direct
Matar AJ, Riad S, Sarumi H, Megaly MG, Wright M, Finger E, Humphreville V, Ramanathan K, Fisher J, Rao JS, Demko Z, Prewett A, Tabriziani H, Kandaswamy R.   +13 more
europepmc   +1 more source

Adherence of cell-free DNA noninvasive prenatal screens to ACMG recommendations

, 2019
Brian G. Skotko, Megan Allyse, Komal Bajaj, Robert G. Best, Susan Klugman, Mark W.Leach, Stephanie Meredith, Marsha Michie, Katie Stoll, Anthony R. Gregg   +9 more
openalex   +2 more sources