Results 11 to 20 of about 1,280,222 (240)
Plasma contains ultrashort single-stranded DNA in addition to nucleosomal cell-free DNA
iScience, 2022 Summary: Plasma cell-free DNA is being widely explored as a biomarker for clinical screening. Currently, methods are optimized for the extraction and detection of double-stranded mononucleosomal cell-free DNA of ∼160bp in length. We introduce uscfDNA-seq,
Jordan Cheng +13 more
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Plasma Cell-Free DNA After Embolization
Journal of Vascular Anomalies, 2023 Objectives:. To identify genetic variants in venous malformations for noninvasive diagnosis using peripheral plasma Cell-free DNA (cfDNA) after ethanol embolization. Method:.
Yi Sun +10 more
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Biomarker Research, 2023 Background Recent advances in circulating cell-free DNA (cfDNA) analysis from biofluids have opened new avenues for liquid biopsy (LB). However, current cfDNA LB assays are limited by the availability of existing information on established genotypes ...
Neeti Swarup +14 more
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Кардиоваскулярная терапия и профилактика, 2022 The search for early disease markers and the development of diagnostic systems has recently been expanding within genomics. Genomic deoxyribonucleic acid (DNA), cell-free DNA (cfDNA) and microbiome DNA obtained from different types of samples (tissues ...
V. A. Kondratskaya +6 more
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Endogenous cell-free DNA in fetal bovine serum introduces artifacts to in vitro cell-free DNA models
BioTechniques, 2022 Cell-free DNA (cfDNA) is of growing clinical and research significance. In vitro cfDNA models are a useful tool in cfDNA research; however, artifacts in these models may have implications for the interpretation of new and published data.
Bonnita Werner +2 more
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Frontiers in Oncology, 2018 BackgroundCell-free DNA (cfDNA) can be detected in the circulation of healthy individuals, but is found in higher concentrations in cancer patients. Furthermore, mutations in tumor cells can be identified in circulating DNA fragments.
Jonathan M. Fussey +9 more
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Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers
Cells, 2019 As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders.
Valentina Karin-Kujundzic +8 more
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Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content
BMC Cancer, 2022 Background Circulating cell-free DNA (cfDNA) in the plasma of cancer patients contains cell-free tumour DNA (ctDNA) derived from tumour cells and it has been widely recognized as a non-invasive source of tumour DNA for diagnosis and prognosis of cancer ...
Devika Ganesamoorthy +9 more
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Comparison of methods for the isolation of cell-free DNA from cell culture supernatant
Tumor Biology, 2020 In vitro characterization of cell-free DNA using two-dimensional cell culture models is emerging as an important step toward an improved understanding of the physical and biological characteristics of cell-free DNA in human biology.
Abel Jacobus Bronkhorst +2 more
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Balkan Medical Journal, 2020 Background: Cell-free DNA, which may be considered as “liquid” biopsy, may serve as a diagnostic and prognostic marker not only in hematological malignancies but in solid tumors as well.
Zeynep Arzu Yegin +6 more
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